{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T00:05:52Z","timestamp":1700611552086},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,1,10]],"date-time":"2012-01-10T00:00:00Z","timestamp":1326153600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2012,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content>Background<\/jats:styled-content>: Current \u201cbest\u201d medical therapy with anti\u2010platelet and\/or anti\u2010thrombotic agents for symptomatic atherosclerotic intracranial (IC) disease is associated with high recurrence. IC catheter\u2010based therapy (CBT) using balloon angioplasty with or without stent placement is an option for patients who have failed medical therapy. We sought to examine the outcomes of CBT for patients with symptomatic IC arterial disease managed by experienced interventional cardiologists. <jats:styled-content>Methods<\/jats:styled-content>: We retrospectively studied 89 consecutive symptomatic patients with 99 significant (\u226570% diameter) IC arterial stenoses who underwent CBT. CBT was performed by experienced interventional cardiologists with the consultative support of a neurovascular team. The primary endpoint was stroke and vascular death. <jats:styled-content>Results<\/jats:styled-content>: Procedure success was achieved in 96\/99 (97%) lesions and percent diameter stenosis was reduced from 91% \u00b1 7.5% preprocedure to 19% \u00b1 15% postprocedure (<jats:italic>P<\/jats:italic> &lt; 0.001). The rate of in\u2010hospital periprocedural stroke and all death was 3%. The primary endpoint of stroke and vascular death rate at 1 year was 5.7% (5\/88) and at 2 years was 13.5% (11\/81). The 2\u2010year all\u2010cause mortality was 11.3% (10\/88). <jats:styled-content>Conclusions<\/jats:styled-content>: For patients with symptomatic IC arterial stenosis who have failed medical therapy or are considered very high risk for stroke, CBT performed by experienced interventional cardiologists is safe and offers both high procedural success rates and excellent clinical outcomes at 1 year. CBT is an attractive option for this high\u2010risk patient population considering the expected 12\u201315% rate of recurrent stroke at 1 year. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/ccd.23439","type":"journal-article","created":{"date-parts":[[2011,11,25]],"date-time":"2011-11-25T06:20:40Z","timestamp":1322202040000},"page":"121-127","source":"Crossref","is-referenced-by-count":2,"title":["Elective percutaneous intervention for intracranial atherosclerotic stenoses by interventional cardiologists"],"prefix":"10.1002","volume":"80","author":[{"given":"Ramy A.","family":"Badawi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher J.","family":"White","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tyrone J.","family":"Collins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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