{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T23:03:12Z","timestamp":1776121392009,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,3,15]],"date-time":"2012-03-15T00:00:00Z","timestamp":1331769600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title><jats:styled-content>Objectives<\/jats:styled-content><\/jats:title><jats:p>The aim of the study is to evaluate the safety and effectiveness of treating femoropopliteal in\u2010stent restenosis (ISR) with debulking with excimer laser followed by implantation of a VIABAHN endoprosthesis.<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:styled-content>Background<\/jats:styled-content><\/jats:title><jats:p>The optimal treatment strategy for femoropopliteal ISR is unclear.<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:styled-content>Methods<\/jats:styled-content><\/jats:title><jats:p>The SALVAGE study is a multicenter prospective registry involving nine US centers. Patients with femoropopliteal ISR with moderate to severe intermittent claudication or critical limb ischemia (Rutherford categories 2\u20135) and an ankle\u2010brachial index (ABI) =0.8 were treated with excimer laser and the VIABAHN endoprosthesis. The primary efficacy endpoint is primary patency at 12 months as measured by duplex ultrasonography. The primary safety endpoint is the major adverse event (MAE) rate at 30 days.<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:styled-content>Results<\/jats:styled-content><\/jats:title><jats:p>Twenty\u2010seven patients were enrolled. The mean lesion length was 20.7 \u00b1 10.3 cm. The majority of lesions were TASC (TASC I) C and D (81.4%). All lesions were pretreated with excimer laser and percutaneous transluminal angioplasty (PTA) prior to VIABAHN implantation. Technical success was achieved in 100% of cases. There were no MAE at 30 days. Primary patency at 12 months was 48%. The ankle brachial index increased from 0.58 \u00b1 0.24 at baseline to 0.90 \u00b1 0.17 at 12 months. There was improvement in all quality\u2010of\u2010life parameters. The 12\u2010month TLR rate was 17.4%.<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:styled-content>Conclusions<\/jats:styled-content><\/jats:title><jats:p>The strategy of excimer laser atherectomy and PTA followed by implantation of a self\u2010expanding stent graft for the treatment of femoropopliteal ISR is safe and associated with high procedural success. Primary patency rate at 12\u2010months was suboptimal; however, the TLR rate was low. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.23475","type":"journal-article","created":{"date-parts":[[2012,3,15]],"date-time":"2012-03-15T19:17:24Z","timestamp":1331839044000},"page":"852-859","source":"Crossref","is-referenced-by-count":49,"title":["Excimer laser with adjunctive balloon angioplasty and heparin\u2010coated self\u2010expanding stent grafts for the treatment of femoropopliteal artery in\u2010stent restenosis"],"prefix":"10.1002","volume":"80","author":[{"suffix":"Jr.","given":"John R.","family":"Laird","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khung Keong","family":"Yeo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krishna","family":"Rocha\u2010Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tony","family":"Das","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Joye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Dippel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhagat","family":"Reddy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"Botti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael R.","family":"Jaff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,3,15]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.688341"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa051303"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1583\/04-1359.1"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.109.903468"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1583\/1545-1550(2003)010<0619:PTOLSF>2.0.CO;2"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1583\/05-1799.1"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.RVI.0000052290.26939.cb"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.217.1.r00se0595"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2005.04.027"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(97)70045-4"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.21104"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.92.3.614"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(98)70034-5"},{"issue":"1","key":"e_1_2_6_15_2","first-page":"S1","article-title":"Management of peripheral arterial disease (PAD). 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