{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T11:32:04Z","timestamp":1790767924795,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2012,4,17]],"date-time":"2012-04-17T00:00:00Z","timestamp":1334620800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:p>This case aims to describe the hemodynamic effects of intra\u2010aortic balloon pump (IABP) in patients with ventricular septal defect (VSD) complicating myocardial infarction (MI). A 79\u2010year\u2010old man with no previous cardiovascular history presented to the emergency department with subacute inferior myocardial infarction associated with mild signs of systemic hypoperfusion. A transthoracic echocardiography revealed a large akinesia of the left ventricular inferior wall with preserved global left ventricular ejection fraction, as well as a large VSD in the midinferior portion of the interventricular septum. Coronary angiography showed an occlusion of the mid portion of a dominant circumflex coronary artery. The invasive hemodynamic evaluation showed a sizable left\u2010to\u2010right shunt (<jats:italic>Q<\/jats:italic><jats:sub>p<\/jats:sub>\/<jats:italic>Q<\/jats:italic><jats:sub>s<\/jats:sub> = 3.1). Activation of the IABP led to an immediate reduction of the shunt (<jats:italic>Q<\/jats:italic><jats:sub>p<\/jats:sub>\/<jats:italic>Q<\/jats:italic><jats:sub>s<\/jats:sub> = 2.4 = 22% reduction), an increase in systemic cardiac output (from 2.1 L\/min to 2.4 L\/min = +12%) and a decrease in the systemic vascular resistances (from 2240 to 1920 dyne\u2010sec\/cm<jats:sup>5<\/jats:sup> = 15% reduction). In patients with post\u2010MI VSD, placement of IABP leads to an immediate reduction in left\u2010to\u2010right shunt and as a consequence to an increase in systemic cardiac output, which may allow hemodynamic stabilization of the patient prior to surgical VSD closure. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/ccd.24290","type":"journal-article","created":{"date-parts":[[2012,4,17]],"date-time":"2012-04-17T19:59:22Z","timestamp":1334692762000},"page":"727-731","source":"Crossref","is-referenced-by-count":10,"title":["Left\u2010to\u2010right shunt reduction with intra\u2010aortic balloon pump in postmyocardial infarction ventricular septal defect"],"prefix":"10.1002","volume":"81","author":[{"given":"Ariane","family":"Testuz","sequence":"first","affiliation":[{"name":"Cardiology Division Geneva University Hospitals Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Roffi","sequence":"additional","affiliation":[{"name":"Cardiology Division Geneva University Hospitals Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert Francis","family":"Bonvini","sequence":"additional","affiliation":[{"name":"Cardiology Division Geneva University Hospitals Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,4,17]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197305102881901"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn602"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.11.070"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(62)90012-1"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(96)00034-4"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn416"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000134791.68010.FA"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1962.03620180093011"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.101.1.27"},{"issue":"4","key":"e_1_2_4_11_1","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/S0022-5223(19)33699-2","article-title":"Late functional results after surgical closure of acquired ventricular septal defect","volume":"106","author":"Davies RH","year":"1993","journal-title":"J Thorac Cardiovasc Surg"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(00)00482-6"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2004.10.037"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra020228"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn524"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.47.6.1191"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(03)00665-9"},{"key":"e_1_2_4_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001010050128"},{"key":"e_1_2_4_19_1","first-page":"246","volume":"64","author":"Cigarroa RG","year":"1989","journal-title":"Oximetric quantitation of intracardiac left\u2010to\u2010right shunting: Limitations of the QpQs ratio Am J Cardiol"},{"key":"e_1_2_4_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(10)61449-X"},{"key":"e_1_2_4_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(92)91346-B"},{"key":"e_1_2_4_22_1","first-page":"693","article-title":"Transcatheter closure of postinfarction ventricular septal defects","volume":"55","author":"Kaulfersch C","year":"2007","journal-title":"Minerva Cardioangiol"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.24290","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.24290","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T17:03:10Z","timestamp":1700672590000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.24290"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4,17]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["10.1002\/ccd.24290"],"URL":"https:\/\/doi.org\/10.1002\/ccd.24290","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,17]]}}}