{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T09:56:40Z","timestamp":1696586200858},"reference-count":17,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,6,3]],"date-time":"2013-06-03T00:00:00Z","timestamp":1370217600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this observational, multicenter study was to describe the outcome of very elderly patients undergoing percutaneous coronary intervention (PCI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>There is a paucity of data among nonagenarians undergoing PCI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All consecutive patients 90 years of age or older undergoing PCI with stent implantation between April 2002 and June 2009 were included in the study. The primary endpoint was the long\u2010term rate of net adverse cardiac events (NACE), that is, death, myocardial infarction (MI), target lesion revascularization, and life\u2010threatening or major bleedings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred forty\u2010six nonagenarians were divided in three groups according to clinical setting: 27 (group A) stable angina or silent ischemia, 85 (group B) unstable angina or non\u2010ST elevation MI, and 34 (group C) with ST elevation MI (STEMI). At 30 days, the incidence of NACE was significantly lower in patients in Group A vs. B or C (0% vs. 17.3% vs. 31.2%, <jats:italic>P<\/jats:italic> = 0.006), and the frequency of definite stent thrombosis was higher in Group C vs. A or B (9.4% vs. 0% vs. 0%, <jats:italic>P<\/jats:italic> = 0.007), respectively. Up to a median follow\u2010up of 24 months, NACE rate was 33.3% in group A, 49.3% in group B, and 50% in group C (<jats:italic>P<\/jats:italic> = 0.32). There were no significant differences between groups in the individual components of the primary endpoint.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>PCI in nonagenarians is safe and feasible with acceptable major bleeding rates. However, long\u2010term results show high mortality rates particularly in the STEMI group. \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.24406","type":"journal-article","created":{"date-parts":[[2012,4,19]],"date-time":"2012-04-19T12:13:31Z","timestamp":1334837611000},"page":"414-421","source":"Crossref","is-referenced-by-count":4,"title":["Retrospective multicenter observational study of the interventional management of coronary disease in the very elderly: The NINETY"],"prefix":"10.1002","volume":"82","author":[{"given":"Dario","family":"Sillano","sequence":"first","affiliation":[{"name":"Division of Interventional Cardiology University of Turin Turin Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Resmini","sequence":"additional","affiliation":[{"name":"Division of Interventional Cardiology University of Turin Turin 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