{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T03:00:23Z","timestamp":1761102023242},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,4,23]],"date-time":"2012-04-23T00:00:00Z","timestamp":1335139200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study aimed to analyze the use of everolimus\u2010eluting stents (EES) and paclitaxel\u2010eluting stents (PES) in an unrestricted diabetic population and to compare the performance of these two drug\u2010eluting stents.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>EES have demonstrated superiority in efficacy when compared to PES in a general population. However, it is controversial whether this superiority holds true in a diabetic population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From March 2004 to May 2010, 968 patients with consecutive diabetes who underwent percutaneous coronary intervention and implantation of an EES (<jats:italic>n<\/jats:italic> = 388) or PES (<jats:italic>n<\/jats:italic> = 580) at our institution. In\u2010hospital, 1\u2010month, 6\u2010month, and 1\u2010year clinical outcomes were analyzed and compared. Correlates of major adverse cardiac events (MACE) were identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Baseline clinical characteristics were similar between stent types except for more family history of coronary artery disease in the PES group and more insulin\u2010dependent diabetes and unstable angina at initial diagnosis in the EES group. The PES group had higher number of lesions treated, longer stents used, and a higher proportion of intravascular ultrasound and glycoprotein IIb\/IIIa inhibitor use. The EES group had more type C and distal lesions. There was higher target lesion revascularization (TLR)\u2010MACE in the PES group (3.3% vs. 1.0%, <jats:italic>P<\/jats:italic> = 0.03) as well as a higher rate of stent thrombosis (ST) (8 patients vs. 0 in the EES group, <jats:italic>P<\/jats:italic> = 0.03). ST continued to be higher in the PES group at 6 and 12 months and mortality was higher at 12 months in the PES group (9.4% vs. 5.2%, <jats:italic>P<\/jats:italic> = 0.02). After adjustment, no significant differences were found between stent types on Cox regression analysis for hazard ratios at 1\u2010year follow\u2010up of TLR\u2010MACE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In a diabetic population undergoing PCI, the use of an EES compared to PES was associated with lower rates of stent thrombosis; but after adjustment the composite TLR\u2010MACE at 1 year was similar between both stents. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.24438","type":"journal-article","created":{"date-parts":[[2012,4,3]],"date-time":"2012-04-03T21:57:46Z","timestamp":1333490266000},"page":"759-765","source":"Crossref","is-referenced-by-count":4,"title":["Safety and efficacy of everolimus\u2010eluting stents versus paclitaxel\u2010eluting stents in a diabetic population"],"prefix":"10.1002","volume":"81","author":[{"given":"Ana","family":"Laynez","sequence":"first","affiliation":[{"name":"Department of Cardiology Washington Hospital Center Washington District of Columbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel","family":"Sardi","sequence":"additional","affiliation":[{"name":"Department of Cardiology Washington Hospital Center Washington District of Columbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camille","family":"Hauville","sequence":"additional","affiliation":[{"name":"Department of Cardiology Washington Hospital Center Washington District of Columbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Israel M.","family":"Barbash","sequence":"additional","affiliation":[{"name":"Department of Cardiology Washington Hospital Center Washington District of Columbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajbabu","family":"Pakala","sequence":"additional","affiliation":[{"name":"Department of Cardiology Washington Hospital Center Washington District of 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Columbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ron","family":"Waksman","sequence":"additional","affiliation":[{"name":"Department of Cardiology Washington Hospital Center Washington District of Columbia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,4,23]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/S0735-1097(02)01971-X","article-title":"Effects of coronary stenting on vessel patency and long\u2010term clinical outcome after percutaneous coronary revascularization in diabetic patients","volume":"40","author":"Belle E","year":"2002","journal-title":"J Am Coll 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