{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T03:00:00Z","timestamp":1761102000650},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,11,8]],"date-time":"2012-11-08T00:00:00Z","timestamp":1352332800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Drug\u2010eluting stents (DES) are more effective in reducing restenosis than bare\u2010metal stents. Less certain is the relative performance of the two widely used DES\u2014sirolimus\u2010eluting stents (SES) and paclitaxel\u2010eluting stents (PES)\u2014in diabetic patients undergoing percutaneous coronary intervention (PCI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We studied the long\u2010term effectiveness and safety of SES versus PES in diabetic patients, overall and grouped by the size of the stent placed in the native\u2010stented vessel.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data were obtained from an observational, multicenter registry of 2,429 consecutive patients with DM who underwent PCI between August 2003 and August 2009 with SES (<jats:italic>n<\/jats:italic> = 1,370) or PES (<jats:italic>n<\/jats:italic> = 1,059). Data were analyzed separately for patients with small stents (&lt;3.0 mm, <jats:italic>n<\/jats:italic> = 1,274) vs. only large (\u22653.0 mm, <jats:italic>n<\/jats:italic> = 1,155).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At Cox\u2010adjusted analysis of the overall cohort, there was no significant difference between SES and PES with regard to death\/myocardial infarction (D\/MI) (<jats:italic>P<\/jats:italic> = 0.6) or target lesion revascularization (TLR) (<jats:italic>P<\/jats:italic> = 0.3) either in \u201csmall\u2010stent\u201d (D\/MI, <jats:italic>P<\/jats:italic> = 0.8; TLR, <jats:italic>P<\/jats:italic> = 0.2) or \u201clarge stent\u201d group (D\/MI, <jats:italic>P<\/jats:italic> = 0.8; TLR, <jats:italic>P<\/jats:italic> = 0.4) throughout 1 to 5\u2010year follow\u2010up. These results were confirmed by sensitivity, propensity\u2010score matched analysis (717 matched pairs) that failed to find differences in the safety and efficacy between SES and PES.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this large observational study, PES and SES were equally safe and efficacious in diabetic patients undergoing PCI in clinical practice, regardless of the stent size. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.24445","type":"journal-article","created":{"date-parts":[[2012,4,18]],"date-time":"2012-04-18T10:30:07Z","timestamp":1334745007000},"page":"80-89","source":"Crossref","is-referenced-by-count":10,"title":["Paclitaxel versus sirolimus eluting stents in diabetic patients: Does stent type and\/or stent diameter matter?: Long\u2010term clinical outcome of 2,429\u2010patient multicenter 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