{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T19:10:33Z","timestamp":1791141033085,"version":"4.1.0"},"reference-count":47,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,2,19]],"date-time":"2013-02-19T00:00:00Z","timestamp":1361232000000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>We sought to characterize UK\u2010wide balloon aortic valvuloplasty (BAV) experience in the TAVI era.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>BAV for acquired calcific aortic stenosis is in a phase of renaissance, largely due to the development of transcatheter aortic valve implantation (TAVI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data from 423 patients at 14 centers across the UK were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients were aged 80.9 \u00b1 9.5 years; 52.5% were male. Mean logistic EuroScore was 27.3% \u00b1 16.8%. Mean peak transaortic gradient fell from 62.0 \u00b1 26.3 to 28.3 \u00b1 16.2 mm Hg. Aortic valve area increased from 0.58 \u00b1 0.19 to 0.80 \u00b1 0.25 cm<jats:sup>2<\/jats:sup> echocardiographically. Procedural complication rate was 6.3%, comprising death (2.4%), blood transfusion \u22652 U (1.2%), cardiac tamponade (1.0%), stroke (1.0%), vascular surgical repair (1.0%), coronary embolism (0.5%), and permanent pacemaker (0.2%). Mortality was 13.8% at 30 days and 36.3% at 12 months. Subsequently, 18.3% of patients underwent TAVI and 7.0% sAVR, with improved survival compared to those who had no further intervention (logrank &lt; 0.0001). Multivariate Cox proportional hazard analysis demonstrated that survival was adversely effected by the presence of coronary artery disease (HR 1.53, 95%CI 1.08\u20132.17, <jats:italic>P<\/jats:italic> = 0.018), poor LV function (HR 1.54, 95%CI 1.09\u20132.16, <jats:italic>P<\/jats:italic> = 0.014), and either urgent (HR 1.70, 95%CI 1.18\u20132.45; <jats:italic>P<\/jats:italic> = 0.004) or emergent presentation (HR 3.72, 95%CI 2.27\u20136.08; <jats:italic>P<\/jats:italic> &lt; 0.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Balloon aortic valvuloplasty offers good immediate hemodynamic efficacy at an acceptable risk of major complications. Medium\u2010term prognosis is poor in the absence of definitive therapy. \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.24534","type":"journal-article","created":{"date-parts":[[2012,6,23]],"date-time":"2012-06-23T04:29:08Z","timestamp":1340425748000},"page":"366-373","source":"Crossref","is-referenced-by-count":50,"title":["Standalone balloon aortic valvuloplasty: Indications and outcomes from the UK in the transcatheter valve era"],"prefix":"10.1002","volume":"81","author":[{"given":"Muhammed Z.","family":"Khawaja","sequence":"first","affiliation":[{"name":"Cardiovascular Division BHF Center of Excellence King's College London St Thomas' Hospital London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manav","family":"Sohal","sequence":"additional","affiliation":[{"name":"Department of Cardiology Sussex Cardiac Center Brighton and Sussex University Hospitals Brighton United 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