{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T23:53:21Z","timestamp":1768348401451,"version":"3.49.0"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,2,12]],"date-time":"2013-02-12T00:00:00Z","timestamp":1360627200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Supra\u2010normal ankle brachial index (ABI) (&gt;1.40), poses diagnostic challenges to determine the presence, location, and severity of peripheral artery disease (PAD). The anatomic distribution of PAD in patients with elevated ABI has not been previously described.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective review of all patients referred to the Massachusetts General Hospital vascular diagnostic laboratory from 5 January 2006 to 12 January 2011 who had both a supra\u2010normal ABI and contrast arteriography (CA) within 3 months of each other is reported. Angiographic patterns were described using the Trans Atlantic Inter Society Consensus II (TASC II) classification.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One\u2010hundred sixteen limbs were analyzed in 92 patients. Mean age was 71.6 years (\u00b111.2); 81.5% (75\/92) were male; 85.9% Caucasian (79\/92); 67.4% diabetics (62\/92); 78.3% hypertensive (72\/92); 67.4% hypercholesterolemic (62\/92); and 64.1% were current or former tobacco users (59\/92). Chronic hemodialysis was present in 18.5% (17\/92) and 15.2% (14\/92) received chronic corticosteroids. Intermittent claudication was present in 46.7% (43\/92) and critical limb ischemia in 52.2% (48\/92). Aortoiliac, femoral and infra\u2010popliteal involvement per angiography occurred in 14.9% (15\/101), 56.1% (60\/107), and 84.0% (84\/100), respectively. Multilevel disease was present in 48.8% (42\/86) of patients. PAD was absent in 4.7% (4\/86) of patients. Toe brachial index &lt;0.7 was found in 92% (92\/100) of patients with angiographically confirmed PAD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In symptomatic patients referred to a vascular laboratory who were found to have supra\u2010normal ABI, nearly one half exhibited multilevel PAD, and over 80% had infrapopliteal involvement. A supra\u2010normal ABI in such patients mandates evaluation for the presence and extent of PAD. \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.24604","type":"journal-article","created":{"date-parts":[[2012,8,17]],"date-time":"2012-08-17T05:29:12Z","timestamp":1345181352000},"page":"1025-1030","source":"Crossref","is-referenced-by-count":23,"title":["Anatomic correlates of supra\u2010normal ankle brachial indices"],"prefix":"10.1002","volume":"81","author":[{"given":"Ido","family":"Weinberg","sequence":"first","affiliation":[{"name":"Section of Vascular Medicine Division of Cardiovascular Medicine The Massachusetts General Hospital Vascular Center Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jay","family":"Giri","sequence":"additional","affiliation":[{"name":"Section of Vascular Medicine Division of Cardiovascular Medicine The Massachusetts General Hospital Vascular Center Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcella A.","family":"Calfon","sequence":"additional","affiliation":[{"name":"Section of Vascular Medicine Division of Cardiovascular Medicine The Massachusetts General Hospital Vascular Center Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beau M.","family":"Hawkins","sequence":"additional","affiliation":[{"name":"Section of Vascular Medicine Division of Cardiovascular Medicine The Massachusetts General Hospital Vascular Center Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitchell D.","family":"Weinberg","sequence":"additional","affiliation":[{"name":"Section of Vascular Medicine Division of Cardiovascular Medicine The Massachusetts General Hospital Vascular Center Boston 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