{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:25:24Z","timestamp":1761863124634},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,3,18]],"date-time":"2013-03-18T00:00:00Z","timestamp":1363564800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Two transcatheter pulmonary valve replacement (tPVR) systems (Edwards SAPIEN and Medtronic Melody) are available; however, comparative studies evaluating outcome data are lacking. The aim of this study was to compare short\u2010 with medium\u2010term outcome data of these valves in the pulmonary position from a single institution.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective data analysis of all patients undergoing tPVR from April 2008 until April 2012. Pre\u2010procedural investigations, patient demographics, procedural hemodynamics, and clinical and echocardiographic follow\u2010up data were included. Data are presented as mean \u00b1 standard deviation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010three patients underwent successful tPVR (SAPIEN (S) <jats:italic>n<\/jats:italic> = 20, Melody (M) <jats:italic>n<\/jats:italic> = 13). Patient age and weight were similar between the two groups. Primary indication included regurgitation (S (<jats:italic>n<\/jats:italic> = 2), M (<jats:italic>n<\/jats:italic> = 3)), stenosis (S (<jats:italic>n<\/jats:italic> = 13), M (<jats:italic>n<\/jats:italic> = 7)), or mixed (S (<jats:italic>n<\/jats:italic> = 5), M (<jats:italic>n<\/jats:italic> = 3)). There was no difference in pre\u2010procedural peak Doppler gradients across the pulmonary outflow (S = 47.73 \u00b1 21.14 mm Hg, M = 42.62 \u00b1 15.59 mm Hg, <jats:italic>P<\/jats:italic> = 0.46). All but one patient underwent pre\u2010stenting prior to valve implantation. Immediately following valve deployment, the transvalvar gradient was not statistically different between the two groups (S = 11.5 \u00b1 8.07 mm Hg, M = 8.15 \u00b1 4.56 mm Hg, <jats:italic>P<\/jats:italic> = 0.18). There were no procedural deaths. Follow\u2010up mean pulmonary Doppler gradients were higher with the SAPIEN cohort (18.43 \u00b1 9.06 mm Hg (S) and 11.17 \u00b1 5.24 mm Hg (M), <jats:italic>P<\/jats:italic> = 0.016); however, no differences were seen when similar procedural epochs were assessed. All but one patient remained with PR grade = 2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In a single\u2010center series, the SAPIEN and Melody valves demonstrated comparable medium\u2010term valve function. Greater residual gradients with the SAPIEN valve may represent a more conservative early pre\u2010stenting approach with this valve. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.24680","type":"journal-article","created":{"date-parts":[[2012,9,25]],"date-time":"2012-09-25T16:58:12Z","timestamp":1348592292000},"source":"Crossref","is-referenced-by-count":29,"title":["Single\u2010center comparative outcomes of the edwards SAPIEN and medtronic melody transcatheter heart valves in the pulmonary position"],"prefix":"10.1002","volume":"82","author":[{"given":"Nadeen","family":"Faza","sequence":"first","affiliation":[{"name":"Rush Center for Congenital and Structural Heart Disease Rush University Medical Center Chicago IL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damien","family":"Kenny","sequence":"additional","affiliation":[{"name":"Rush Center for Congenital and Structural Heart Disease Rush University Medical Center Chicago IL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clifford","family":"Kavinsky","sequence":"additional","affiliation":[{"name":"Rush Center for Congenital and Structural Heart Disease Rush University Medical Center Chicago IL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zahid","family":"Amin","sequence":"additional","affiliation":[{"name":"Rush Center for Congenital and Structural Heart Disease Rush University Medical Center Chicago IL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Heitschmidt","sequence":"additional","affiliation":[{"name":"Rush Center for Congenital and Structural Heart Disease Rush University Medical Center Chicago IL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziyad M.","family":"Hijazi","sequence":"additional","affiliation":[{"name":"Rush Center for Congenital and Structural Heart Disease Rush University Medical Center Chicago IL"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,3,18]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehl033"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2007.04.104"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.523266"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.921692"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.07.040"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.06.034"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.735779"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.22653"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2010.198382"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.111.965616"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2007.12.034"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq520"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.582882"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1008232"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.22250"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1202277"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1200384"},{"key":"e_1_2_7_19_1","article-title":"Percutaneous implantation of Edwards SAPIEN valve into pulmonary bioprosthesis (valve\u2010in\u2010valve)","author":"Lombardi M","year":"2012","journal-title":"J Cardiovasc Med (Hagerstown)"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.24680","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.24680","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T08:20:00Z","timestamp":1696580400000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.24680"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,18]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["10.1002\/ccd.24680"],"URL":"https:\/\/doi.org\/10.1002\/ccd.24680","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,18]]}}}