{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T04:09:33Z","timestamp":1761970173142,"version":"build-2065373602"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,2,26]],"date-time":"2013-02-26T00:00:00Z","timestamp":1361836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To determine the prevalence of a concurrent CTO in men and women and to examine its impact on mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>The impact of chronic total occlusion (CTO) in patients with ST\u2010elevation myocardial infarction (STEMI) according to gender has not been assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients referred with STEMI were categorized into single vessel disease (SVD), multivessel disease (MVD) without, with 1 or &gt; 1 CTO. The primary end\u2010point was the 1\u2010year mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 2020 STEMI patients included between 2006 and 2011, 24% were female. Women were older, had more hypertension and renal failure (<jats:italic>P<\/jats:italic> &lt; 0.0001 for all). The prevalence of 1 or &gt; 1 concurrent CTO was similar in both sexes, 7 and 1%, respectively. Early and late mortality was significantly higher in women compared with men (<jats:italic>P<\/jats:italic> &lt; 0.0001). In women, the mortality was significantly worse in patients with &gt; 1 CTO (100%) and with 1 CTO (36.4%) compared with those with MVD without CTO (18.4%) or with SVD (10.4%) (<jats:italic>P<\/jats:italic> &lt; 0.0001). MVD with and without concurrent CTO were both independent predictors of 1\u2010year mortality in women (HR 3.58; 95 % CI 1.69\u20137.18 and HR 2.76; 95 % CI 1.33\u20135.51) whereas only MVD with CTO was predictive in men (HR 2.19; 95% CI 1.20\u20133.97).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Among unselected STEMI patients, the prevalence of CTO was equal in both sexes whereas early and late mortality remained significantly higher in women. Other factors than the presence of a concurrent CTO must be explored to explain differences in survival after STEMI between women and men. \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.24697","type":"journal-article","created":{"date-parts":[[2012,10,16]],"date-time":"2012-10-16T16:06:43Z","timestamp":1350403603000},"page":"19-26","source":"Crossref","is-referenced-by-count":10,"title":["Incidence and clinical impact of concurrent chronic total occlusion according to gender in ST\u2010Elevation myocardial infarction"],"prefix":"10.1002","volume":"82","author":[{"given":"Yoann","family":"Bataille","sequence":"first","affiliation":[{"name":"Department of Cardiology Quebec Heart-Lung Institute 2725, chemin Ste Foy Quebec City Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean\u2010Pierre","family":"D\u00e9ry","sequence":"additional","affiliation":[{"name":"Department of Cardiology Quebec Heart-Lung Institute 2725, chemin Ste Foy Quebec City Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c9ric","family":"Larose","sequence":"additional","affiliation":[{"name":"Department of Cardiology Quebec Heart-Lung Institute 2725, chemin Ste Foy Quebec City Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eltigani","family":"Abdelaal","sequence":"additional","affiliation":[{"name":"Department of Cardiology Quebec Heart-Lung Institute 2725, chemin Ste Foy Quebec City Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jimmy","family":"Machaalany","sequence":"additional","affiliation":[{"name":"Department of Cardiology Quebec Heart-Lung Institute 2725, chemin Ste Foy Quebec City Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josep","family":"Rod\u00e9s\u2010Cabau","sequence":"additional","affiliation":[{"name":"Department of Cardiology Quebec Heart-Lung Institute 2725, chemin Ste Foy Quebec City Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"St\u00e9phane","family":"Rinfret","sequence":"additional","affiliation":[{"name":"Department of Cardiology Quebec Heart-Lung Institute 2725, chemin Ste Foy Quebec City Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ugo","family":"D\u00e9ry","sequence":"additional","affiliation":[{"name":"Department of Cardiology Quebec Heart-Lung Institute 2725, chemin Ste Foy Quebec City Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivier","family":"Costerousse","sequence":"additional","affiliation":[{"name":"Department of Cardiology Quebec Heart-Lung Institute 2725, chemin Ste Foy Quebec City Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louis","family":"Roy","sequence":"additional","affiliation":[{"name":"Department of Cardiology Quebec Heart-Lung Institute 2725, chemin Ste Foy Quebec City Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivier F.","family":"Bertrand","sequence":"additional","affiliation":[{"name":"Department of Cardiology Quebec Heart-Lung Institute 2725, chemin Ste Foy Quebec City Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,2,26]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12113-7"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2008.08.012"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acvd.2010.04.002"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV6I9A187"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV6I9A186"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2007.08.044"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2009.08.024"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2009.11.014"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2012.07.008"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.06.010"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.22664"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2011.08.026"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr471"},{"first-page":"64","volume-title":"2001. 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