{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:41:36Z","timestamp":1761561696197},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,12,3]],"date-time":"2012-12-03T00:00:00Z","timestamp":1354492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The biodegradable polymer drug\u2010eluting stents have been proposed as an alternative to durable polymer DES, theoretically improving vessel healing and reducing the need for prolonged double anti platelet therapy (DAPT), however clinical significance of this technology is under debate. Therefore, we sought to compare the clinical outcomes of two Paclitaxel eluting stents (PES) containing different polymer\u2010based eluting matrices.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this multicenter registry of 392 consecutive patients who underwent PCI between June 2006 and September 2008, we included patients with stable angina or NSTE\u2010ACS displaying at least one significant lesion (&gt;50% diameter stenosis) in native coronary arteries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Biodegradable polymer PES (BP\u2010PES, LUC Chopin<jats:sup>2<\/jats:sup>, Balton, Poland) was implanted in 206 patients, whereas durable polymer PES (DP\u2010PES, Taxus, Boston Scientific, USA) was implanted in 186 patients. There were no significant differences in baseline characteristics between groups with the exception of increased diabetes and number of lesions for BP\u2010PES. In risk\u2010unadjusted analysis at 1\u2010year follow\u2010up, there were no significant differences in TLR (BP\u2010PES: 8.4% vs. DP\u2010PES: 6%; <jats:italic>P<\/jats:italic> = 0.36), TVR (BP\u2010PES: 11.1% vs. DP\u2010PES: 8.4%; <jats:italic>P<\/jats:italic> = 0.36) and incidence of stent thromboses (BP\u2010PES: 2.15% vs. DP\u2010PES: 3.4%; <jats:italic>P<\/jats:italic> = 0.42) between groups. There was also no difference in MACCE between groups (17.6% vs. 14.4%, <jats:italic>P<\/jats:italic> = 0.49). The mean dual antiplatelet therapy (DAPT) compliance at 1 year was 77% for BP\u2010PES versus 92% for DP\u2010PES (<jats:italic>P<\/jats:italic> = 0.03). Kaplan\u2013Meier analysis showed a significantly higher long\u2010term stroke free survival in BP\u2010PES (<jats:italic>P<\/jats:italic> = 0.04). After adjustment, this was sustained with an additional tendency toward higher MI free survival for BP\u2010PES (<jats:italic>P<\/jats:italic> = 0.059).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this observational analysis, BP\u2010PES were comparable to DP\u2010PES, with regard to incidence of repeated revascularizations, stent thromboses and MACCE despite earlier DAPT discontinuation. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.24732","type":"journal-article","created":{"date-parts":[[2012,10,29]],"date-time":"2012-10-29T14:41:41Z","timestamp":1351521701000},"source":"Crossref","is-referenced-by-count":5,"title":["Comparable clinical safety and efficacy of biodegradable versus durable polymer paclitaxel eluting stents despite shorter dual antiplatelet therapy: Insights from a multicenter, propensity score\u2010matched registry"],"prefix":"10.1002","volume":"82","author":[{"given":"Piotr P.","family":"Buszman","sequence":"first","affiliation":[{"name":"American Heart of Poland Katowice Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bartlomiej","family":"Orlik","sequence":"additional","affiliation":[{"name":"American Heart of Poland Katowice Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Blazej","family":"Trela","sequence":"additional","affiliation":[{"name":"American Heart of Poland Katowice Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krzysztof","family":"Milewski","sequence":"additional","affiliation":[{"name":"American Heart of Poland Katowice Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michal","family":"Kozlowski","sequence":"additional","affiliation":[{"name":"American Heart of Poland Katowice Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Maciej","family":"Pruski","sequence":"additional","affiliation":[{"name":"American 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