{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T17:15:25Z","timestamp":1780593325249,"version":"3.54.1"},"reference-count":29,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,3,18]],"date-time":"2013-03-18T00:00:00Z","timestamp":1363564800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>We report the results of a large single\u2010center study evaluating predictors and outcomes after transcatheter aortic valve implantation (TAVI) with different devices and access routes according to the Valve Academic Research Consortium (VARC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>The widespread adoption of TAVI warrants a systematic analysis of outcomes. Only few comprehensive data exist comparing different approaches as selected by a heart team.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>TAVI was performed in 326 consecutive patients (mean age 80.6 \u00b1 7.1 years, 55.5% female) at high risk for surgery with balloon\u2010expandable and self\u2010expanding devices through transfemoral or transapical access. Data were analyzed according to VARC endpoints; predictors of mortality were identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All\u2010cause mortality was 10.1% (30 days) and 29.9% (1 year) overall and comparable with regard to valve or access choice (<jats:italic>P<\/jats:italic> = 0.295) despite different risk profiles at baseline. Device success and 30\u2010day safety endpoints were achieved in 87.1 and 21.2%. Myocardial infarction [hazard ratio (HR) 6.52], stage\u20102 and \u22123 acute kidney injury (HR 2.52 and 6.80) and major access site complications (HR 1.96) were independent predictors of 1\u2010year all\u2010cause mortality. Device success had a protective effect (HR 0.58). Baseline predictors included body mass index &lt;20 kg\/m<jats:sup>2<\/jats:sup> (HR 3.20), NYHA class IV (HR 1.87), left ventricular ejection\u2010fraction &lt;30% (HR 2.30), higher STS\u2010PROM scores (HR 1.05 per percent), and age (group 75\u201385 years, HR 0.47).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Comparable results were achieved with different devices and access routes in a heart team approach. Baseline and perioperative predictors of all\u2010cause mortality were identified, contributing to the refinement of patient and device selection criteria for TAVI. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.24751","type":"journal-article","created":{"date-parts":[[2012,11,21]],"date-time":"2012-11-21T20:16:17Z","timestamp":1353528977000},"page":"640-652","source":"Crossref","is-referenced-by-count":44,"title":["Predictors and outcomes after transcatheter aortic valve implantation using different approaches according to the valve academic research consortium definitions"],"prefix":"10.1002","volume":"82","author":[{"given":"Moritz","family":"Seiffert","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery University Heart Center Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renate","family":"Schnabel","sequence":"additional","affiliation":[{"name":"Department of General and Interventional 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