{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T08:48:47Z","timestamp":1768034927420,"version":"3.49.0"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,4,18]],"date-time":"2013-04-18T00:00:00Z","timestamp":1366243200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>To assess the results of transcatheter aortic valve implantation (TAVI) using the Medtronic CoreValve prosthesis (Medtronic, Minneapolis, MN), without balloon predilation, in high\u2010risk patients with degenerated severe aortic stenosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>Fifty\u2010one consecutive patients who underwent direct TAVI, 98% through a transfemoral approach. Patients were 79\u2009\u00b1\u20098 years of age, 74% in New York Heart Association classes III or IV and at high risk for surgical valve replacement (mean logistic EuroScore 20\u2009\u00b1\u200915). Mean aortic valve area was 0.7\u2009\u00b1\u20090.2 cm<jats:sup>2<\/jats:sup>. Procedural success rate was 94.2%. In\u2010hospital, there were 2 deaths, 1 minor stroke with minimal sequelae, and 14 (28%) pacemaker implantation. At 30 days, there was one additional stroke and no new deaths. The mean postprocedural transprosthetic gradient was 15\u2009\u00b1\u20095 mm Hg; periprosthetic severe regurgitation was absent and moderate in one case. After a median follow\u2010up of 7 months, there were five additional deaths (two cardiac), while 84% of survivors were in New York Heart Association classes I or II.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These results suggest that direct CoreValve implantation in patients with severe aortic stenosis is feasible and may lead to hemodynamic and clinical improvement in patients who are poor candidates for aortic valve surgery, pending confirmation in larger series with longer follow\u2010up. \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.24805","type":"journal-article","created":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T06:02:59Z","timestamp":1364796179000},"page":"292-297","source":"Crossref","is-referenced-by-count":19,"title":["Transcatheter aortic valve implantation without balloon predilation: A single\u2010center pilot experience"],"prefix":"10.1002","volume":"82","author":[{"given":"Oscar A.","family":"Mendiz","sequence":"first","affiliation":[{"name":"Department of Interventional Cardiology and Cardiovascular Surgery Hospital Universitario Fundaci\u00f3n Favaloro Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugo","family":"Fraguas","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology and Cardiovascular Surgery Hospital Universitario Fundaci\u00f3n Favaloro Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo A.","family":"Lev","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology and Cardiovascular Surgery Hospital Universitario Fundaci\u00f3n Favaloro Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leon R.","family":"Valdivieso","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology and Cardiovascular Surgery Hospital Universitario Fundaci\u00f3n Favaloro Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto R.","family":"Favaloro","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology and Cardiovascular Surgery Hospital Universitario Fundaci\u00f3n Favaloro Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,4,18]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1008232"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.12.014"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2010.08.014"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8183.2010.00577.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.108.819839"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.12.005"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr491"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1114705"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2012.01.019"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2011.03.015"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.08.050"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.001545"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1103510"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-4949.2012.00804"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2012.01.389"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.09.010"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezs155"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV7I5A92"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2012.02.010"}],"container-title":["Catheterization 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