{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T20:03:33Z","timestamp":1792181013228,"version":"4.4.0"},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,7,11]],"date-time":"2013-07-11T00:00:00Z","timestamp":1373500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare procedural outcomes of transcatheter balloon pulmonary valvuloplasty (BPV) in adults to a concurrent pediatric cohort and to identify whether BPV leads to improvement in symptoms among adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>BPV has long been utilized to relieve right ventricular outflow tract (RVOT) obstruction in neonates and young children. More recently, BPV has been performed in adults, but outcome data are limited in this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We reviewed all cases of BPV performed at Mayo Clinic's Congenital Cardiac Cath Lab from December 1993 to July 2012. Patients were excluded if they had additional congenital heart defects, other than simple left\u2010to\u2010right shunt lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>89 children and 40 adults underwent 132 BPV procedures. Among the adults, 78% were symptomatic at the time of BPV. The most common symptoms were dyspnea and fatigue. RVOT systolic gradient was 42 \u00b1 19 mmHg (children) and 54 \u00b1 26 mmHg (adults) prior to BPV (<jats:italic>P<\/jats:italic> = 0.002). Adults experienced a greater reduction in gradient following BPV (32 \u00b1 21 mmHg vs. 23 \u00b1 19 mmHg; <jats:italic>P<\/jats:italic> = 0.007). No patients exhibited \u201csuicide right ventricle\u201d physiology after BPV. Among adults, mean follow\u2010up was 1.9 years (30 days\u201311 years). Symptoms improved in 20 of the 24 previously symptomatic adults for whom follow\u2010up data were available. Mean NYHA score improved from 2.2 to 1.4 following BPV. At last follow\u2010up, 52% of adults were free of any symptoms, a significant improvement from pre\u2010BPV (<jats:italic>P<\/jats:italic> = 0.0003). Only one patient described worsening of symptoms after BPV.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>BPV is an effective procedure for symptomatic adults with pulmonary valve stenosis. In addition to immediate relief of RVOT gradient, adult patients may experience symptomatic improvement following BPV.\u00a9 2013 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.24973","type":"journal-article","created":{"date-parts":[[2013,4,24]],"date-time":"2013-04-24T08:47:43Z","timestamp":1366793263000},"page":"811-815","source":"Crossref","is-referenced-by-count":15,"title":["Outcomes for balloon pulmonary valvuloplasty in adults: Comparison with a concurrent pediatric cohort"],"prefix":"10.1002","volume":"82","author":[{"given":"Nathaniel W.","family":"Taggart","sequence":"first","affiliation":[{"name":"Division of Pediatric Cardiology Department of Pediatric and Adolescent Medicine Mayo Clinic Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Cetta","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology Department of Pediatric and Adolescent Medicine Mayo Clinic Rochester Minnesota"},{"name":"Division of Cardiovascular Diseases Department of Medicine Mayo Clinic Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison K.","family":"Cabalka","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology Department of Pediatric and Adolescent Medicine Mayo Clinic Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald J.","family":"Hagler","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology Department of Pediatric and Adolescent Medicine Mayo Clinic Rochester Minnesota"},{"name":"Division of Cardiovascular Diseases Department of Medicine Mayo Clinic Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,7,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198208263070907"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(83)90026-7"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.69.3.554"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(84)80360-5"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(84)90140-5"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.89.4.1751"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.80.6.591"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(88)90216-1"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2006.11.021"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.eurheartj.a059555"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(93)90668-Y"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(98)00302-6"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(92)90154-F"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(03)00678-7"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.190690"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e31821b1f10"},{"key":"e_1_2_6_18_1","first-page":"253","volume-title":"Nomenclature and Criteria for Diagnosis of Diseases of the Heart and Great Vessels","author":"The Criteria Committee of the New York Heart Association","year":"1994"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(85)80407-1"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(93)90727-I"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(92)90882-Y"},{"key":"e_1_2_6_22_1","first-page":"I28","article-title":"Second natural history study of congenital heart defects. 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