{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T09:04:36Z","timestamp":1776848676276,"version":"3.51.2"},"reference-count":21,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2013,6,3]],"date-time":"2013-06-03T00:00:00Z","timestamp":1370217600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The purpose of this study was to identify the relationship between angiographic patterns of restenosis and outcomes after endovascular treatment of femoro\u2010popliteal in\u2010stent restenosis (FP\u2010ISR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>ISR is a frequent clinical problem after femoro\u2010popliteal stenting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a single center study of all endovascular interventions for FP\u2010ISR from 2006 to 2012. Class I ISR was defined as focal lesions \u226450 mm; Class II ISR as lesions\u2009&gt;\u200950 mm; and Class III ISR as stent chronic total occlusion. Recurrent ISR was defined as peak systolic velocity ratio\u2009&gt;\u20092.4 by duplex ultrasound.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 75 cases of FP\u2010ISR, 28 (37%) were Class I, 22 (29%) were Class II, and 25 (33%) were Class III. The mean lesion length was 26\u2009mm for Class I, 135\u2009mm for Class II, and 178\u2009mm for Class III ISR. Patients with Class III ISR more frequently had ISR extending into both the superficial femoral and popliteal artery (48% vs. 18%, <jats:italic>P<\/jats:italic>\u2009=\u20090.005). Balloon angioplasty was used most frequently to treat Class I ISR, while adjunctive atherectomy and\/or stenting was used for almost all cases of Class III ISR. During 2\u2010year follow\u2010up, rates of repeat restenosis were 39% for Class I, 67% for Class II, and 72% for Class III ISR (<jats:italic>P<\/jats:italic>\u2009=\u20090.04). Rates of stent occlusion were 8% for Class I, 11% for Class II, and 52% for Class III ISR (<jats:italic>P<\/jats:italic>\u2009=\u20090.009). Class III ISR was associated with significantly increased risk of recurrent ISR (HR 2.4, 95% CI 1.1\u20135.6) and recurrent occlusion (HR 5.8, 95% CI 1.8\u201319.0) compared to other types of ISR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Angiographic patterns of FP\u2010ISR are important determinants of subsequent outcomes. Repeat restenosis and occlusion remain common despite currently available technologies.\u00a9 2013 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.24983","type":"journal-article","created":{"date-parts":[[2013,4,30]],"date-time":"2013-04-30T09:47:37Z","timestamp":1367315257000},"page":"1168-1174","source":"Crossref","is-referenced-by-count":42,"title":["Angiographic characteristics of femoropopliteal in\u2010stent restenosis: Association with long\u2010term outcomes after endovascular intervention"],"prefix":"10.1002","volume":"82","author":[{"given":"Ehrin J.","family":"Armstrong","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Medicine and the Vascular Center University of California Davis Medical Center Sacramento California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satinder","family":"Singh","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine and the Vascular Center University of California Davis Medical Center Sacramento California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gagan D.","family":"Singh","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine and the Vascular Center University of California Davis Medical Center Sacramento California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khung\u2010Keong","family":"Yeo","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine and the Vascular Center University of California Davis Medical Center Sacramento California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaan","family":"Ludder","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine and the Vascular Center University of California Davis Medical Center Sacramento 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