{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:29:07Z","timestamp":1761895747633},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,11,9]],"date-time":"2013-11-09T00:00:00Z","timestamp":1383955200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Renal artery stent revascularization is commonly used for renovascular hypertension. Clinical predictors associated with blood pressure (BP) improvement after renal artery stent revascularization are not well understood.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patient\u2010level data from 901 patients in five prospective multicenter Food and Drug Administration\u2010approved investigational device exemption studies of renal artery stent revascularization was pooled. BP response was defined as reduction of systolic BP (SBP) by <jats:styled-content>&gt;<\/jats:styled-content>10 mm Hg. Stent patency was defined within each study. Associations of BP reduction were determined by logistic regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 901 patients, complete outcome information was available in 527. Of these, 212\/527 (40%) were male, mean age was 63\u2009\u00b1\u200913 years, 196\/544 (36%) were diabetic and 504\/527 (96%) had a SBP\u2009\u2265\u2009140 mm Hg or DBP\u2009\u2265\u200990 mm Hg at baseline. Compared to baseline, 9\u2010month systolic (164\u2009\u00b1\u200921 mm Hg vs. 146\u2009\u00b1\u200922 mm Hg, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001) and diastolic (79\u2009\u00b1\u200913 mm Hg vs. 76\u2009\u00b1\u200912 mm Hg, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001) BP declined significantly. Nine\u2010month stent patency was 90% (305\/339). In a univariate analysis, baseline SBP &gt;150 mm Hg (OR\u2009=\u20094.09, CI\u2009=\u20092.74\u20136.12, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001) was positively associated with BP response following renal artery stent revascularization. In a multivariable analysis, baseline SBP remained associated with a positive BP response (OR\u2009=\u20091.76, CI\u2009=\u20091.53\u20132.03, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In the largest pooled dataset of patients treated with renal artery stent revascularization, SBP and DBP were significantly lower at 9\u2010months. Elevated baseline SBP (&gt;150 mm Hg) was strongly associated with BP reduction after the procedure. \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.25263","type":"journal-article","created":{"date-parts":[[2013,10,21]],"date-time":"2013-10-21T20:06:09Z","timestamp":1382385969000},"page":"603-609","source":"Crossref","is-referenced-by-count":31,"title":["Blood pressure response to renal artery stenting in 901 patients from five prospective multicenter FDA\u2010approved trials"],"prefix":"10.1002","volume":"83","author":[{"given":"Ido","family":"Weinberg","sequence":"first","affiliation":[{"name":"The Institute for Heart, Vascular and Stroke Care, Massachusetts General Hospital Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle J.","family":"Keyes","sequence":"additional","affiliation":[{"name":"The Institute for Heart, Vascular and Stroke Care, Massachusetts General Hospital Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jay","family":"Giri","sequence":"additional","affiliation":[{"name":"Cardiovascular Medicine Division University of Pennsylvania Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin R.","family":"Rogers","sequence":"additional","affiliation":[{"name":"Cardiology Division University of Colorado Denver Colorado"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey W.","family":"Olin","sequence":"additional","affiliation":[{"name":"Zena and Michael A. 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