{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,24]],"date-time":"2025-08-24T01:15:52Z","timestamp":1755998152251},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,2,4]],"date-time":"2014-02-04T00:00:00Z","timestamp":1391472000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:sec><jats:title><jats:styled-content>Objectives<\/jats:styled-content><\/jats:title><jats:p>To determine whether contrast administration was a risk factor for development of acute kidney injury (AKI) in cyanotic congenital heart disease (CHD) patients undergoing cardiopulmonary bypass (CPB).<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:styled-content>Background<\/jats:styled-content><\/jats:title><jats:p>AKI following CPB or contrast administration is well described. In previous studies, administration of contrast prior to CPB has been shown to increase the risk of AKI. Chronic cyanosis leads to glomerular damage and dysfunction, thus potentially placing this population at increased risk of developing AKI following contrast administration prior to CPB.<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:styled-content>Methods<\/jats:styled-content><\/jats:title><jats:p>One hundred twenty\u2010two patients with cyanotic CHD undergoing preoperative cardiac catheterization (PCC) and subsequent CPB at Children's Medical Center of Dallas from January 1, 2007 until November 30, 2010 were identified, looking specifically at bi\u2010directional Glenn (BDG) anastomoses and Fontan procedures. One hundred thirteen patients undergoing PCC\u2009\u2264\u200948 hr prior to and\u2009&gt;\u20095 days prior to CPB were included. Occurrence of AKI following CPB was the primary outcome variable.<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:styled-content>Results<\/jats:styled-content><\/jats:title><jats:p>Logistic regression analysis revealed pre\u2010catheterization serum creatinine was a risk factor for post\u2010CPB AKI (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) in both Fontan and BDG patients. All other variables were not significantly associated with the development of AKI in either BDG or Fontan patients. Length of stay (hospital or ICU) was not different among the groups regardless of the occurrence of AKI.<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:styled-content>Conclusions<\/jats:styled-content><\/jats:title><jats:p>In this study of cyanotic CHD patients, contrast administration within 48 hr prior to CPB was not an additional risk factor for the development of AKI. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.25405","type":"journal-article","created":{"date-parts":[[2014,1,23]],"date-time":"2014-01-23T17:22:06Z","timestamp":1390497726000},"page":"615-619","source":"Crossref","is-referenced-by-count":14,"title":["Incidence of acute kidney injury following cardiac catheterization prior to cardiopulmonary bypass in children"],"prefix":"10.1002","volume":"84","author":[{"given":"Nicholas","family":"Huggins","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of Texas Southwestern Medical Center Dallas Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan","family":"Nugent","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Pediatrics University of Texas Southwestern Medical Center Dallas Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vinai","family":"Modem","sequence":"additional","affiliation":[{"name":"Division of Critical Care Department of Pediatrics University of Texas Southwestern Medical Center Dallas Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph S.","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiothoracic Surgery Department of Cardiovascular and Thoracic Surgery University of Texas Southwestern Medical Center Dallas Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Forbess","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiothoracic Surgery Department of Cardiovascular and Thoracic Surgery University of Texas Southwestern Medical Center Dallas Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Scott","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Pediatrics University of Texas Southwestern Medical Center Dallas Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V. 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