{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T03:35:29Z","timestamp":1762659329238,"version":"build-2065373602"},"reference-count":43,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,5,20]],"date-time":"2014-05-20T00:00:00Z","timestamp":1400544000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aimed to report the outcomes of African Americans (AAs) in the US undergoing transcatheter aortic valve replacement (TAVR) for severe aortic stenosis (AS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Compared to Caucasians, AAs are reported to have poorer outcomes from most cardiovascular diseases, including high complication rates after surgical aortic valve replacement. The outcomes of AAs undergoing TAVR are not well established.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive patients who underwent TAVR were included in this analysis. Patients' baseline characteristics, procedural data, in\u2010hospital\u2010 and long\u2010term outcomes were recorded and a comparison was performed between the AA and Caucasian cohorts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In a cohort of 469 consecutive patients, 51 (10.8%) were AA and 345 (74.5%) were Caucasian. The remaining patients (<jats:italic>n<\/jats:italic>\u2009=\u200973; 15.3%) self\u2010reported their race as \u201cunknown\u201d or were from other races. Most baseline characteristics were similar between the two groups except for less men (33.3 vs. 50.1%; <jats:italic>P<\/jats:italic>\u2009=\u20090.016), a lower mean left ventricular ejection fraction (48.85\u2009\u00b1\u200916.35 vs. 53.24\u2009\u00b1\u200913.41%; <jats:italic>P<\/jats:italic>\u2009=\u20090.04) and lower rates of atrial fibrillation in AAs (15.7 vs.45.4%; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). TAVR procedures in AAs were less frequently performed as part of a clinical trial (60.8 vs. 76.8%; <jats:italic>P<\/jats:italic>\u2009=\u20090.014). Most procedural and periprocedural outcome parameters were similar save for a higher rate of hemodynamic instability and postoperative need for intubation in AAs (10.4 vs. 2.5%; <jats:italic>P<\/jats:italic>\u2009=\u20090.018 and 29.4 vs. 16.9%; P\u2009=\u20090.03, respectively). This did not translate into a difference in mortality between AAs and Caucasians (30\u2010day mortality 9.8 vs. 9.9%; <jats:italic>P<\/jats:italic>\u2009=\u20090.99; 1\u2010year mortality 19.6 vs. 24.3%; <jats:italic>P<\/jats:italic>\u2009=\u20090.458, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Unlike with other cardiovascular interventions, this study demonstrates that AA patients referred for TAVR shared similar risks and outcomes when compared to a Caucasian population. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.25535","type":"journal-article","created":{"date-parts":[[2014,4,30]],"date-time":"2014-04-30T08:46:40Z","timestamp":1398847600000},"page":"640-647","source":"Crossref","is-referenced-by-count":20,"title":["Outcome comparison of African\u2010American and caucasian patients with severe aortic stenosis subjected to transcatheter aortic valve replacement: A single\u2010center experience"],"prefix":"10.1002","volume":"85","author":[{"given":"Sa'ar","family":"Minha","sequence":"first","affiliation":[{"name":"Interventional Cardiology, MedStar Washington Hospital Center Washington DC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Israel M.","family":"Barbash","sequence":"additional","affiliation":[{"name":"Interventional Cardiology, MedStar Washington Hospital Center Washington DC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco A.","family":"Magalhaes","sequence":"additional","affiliation":[{"name":"Interventional Cardiology, MedStar Washington Hospital Center Washington DC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Itsik","family":"Ben\u2010Dor","sequence":"additional","affiliation":[{"name":"Interventional Cardiology, MedStar Washington Hospital Center Washington DC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petros G.","family":"Okubagzi","sequence":"additional","affiliation":[{"name":"Interventional Cardiology, MedStar Washington Hospital Center Washington DC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lakshmana K.","family":"Pendyala","sequence":"additional","affiliation":[{"name":"Interventional Cardiology, MedStar Washington Hospital Center Washington DC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lowell F.","family":"Satler","sequence":"additional","affiliation":[{"name":"Interventional Cardiology, MedStar Washington Hospital Center Washington DC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Augusto D.","family":"Pichard","sequence":"additional","affiliation":[{"name":"Interventional Cardiology, MedStar Washington Hospital Center Washington DC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"Torguson","sequence":"additional","affiliation":[{"name":"Interventional Cardiology, MedStar Washington Hospital Center Washington DC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ron","family":"Waksman","sequence":"additional","affiliation":[{"name":"Interventional Cardiology, MedStar Washington Hospital Center Washington DC"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,5,20]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp575"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)69208-8"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1103510"},{"key":"e_1_2_6_5_1","first-page":"1","article-title":"Deaths: Leading causes for 2000","volume":"50","author":"Anderson RN","year":"2002","journal-title":"Natl Vital Stat Rep"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(97)00089-2"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carrev.2005.12.001"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.057232"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.07.002"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199902253400804"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.25.3137"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(01)01480-1"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000157737.92938.D8"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1008232"},{"key":"e_1_2_6_15_1","unstructured":"U.S National Institue of Health Clinical Trial Database. 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