{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:37:31Z","timestamp":1786977451496,"version":"build-2736575974"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,5,27]],"date-time":"2014-05-27T00:00:00Z","timestamp":1401148800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To study the economic impact on payers and providers of the four main endovascular strategies for the treatment of infrainguinal peripheral artery disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Bare metal stents (BMS), drug\u2010eluting stents (DES), and drug\u2010coated balloons (DCB) are associated with lower target lesion revascularization (TLR) probabilities than percutaneous transluminal angioplasty (PTA), but the economic impact is unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In December 2012, PubMed and Embase were systematically searched for studies with TLR as an endpoint. The 24\u2010month probability of TLR for each treatment was weighted by sample size. A decision\u2010analytic Markov model was used to assess the budget impact from payers' and facility\u2010providers' perspectives of the four index procedure strategies (BMS, DES, DCB, and PTA). Base cases were developed for U.S. Medicare and the German statutory sickness fund perspectives using current 2013 reimbursement rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirteen studies with 2,406 subjects were included. The reported probability of TLR in the identified studies varied widely, particularly following treatment with PTA or BMS. The pooled 24\u2010month probabilities were 14.3%, 19.3%, 28.1%, and 40.3% for DCB, DES, BMS, and PTA, respectively. The drug\u2010eluting strategies had a lower projected budget impact over 24 months compared to BMS and PTA in both the U.S. Medicare (DCB: $10,214; DES: $12,904; uncoated balloons $13,114; BMS $13,802) and German public health care systems (DCB \u20ac3,619; DES \u20ac3,632; BMS \u20ac4,026; PTA \u20ac4,290).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>DCB and DES, compared to BMS and PTA, are associated with lower probabilities of target lesion revascularization and cost savings for U.S. and German payers. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.25536","type":"journal-article","created":{"date-parts":[[2014,4,30]],"date-time":"2014-04-30T05:12:46Z","timestamp":1398834766000},"page":"546-554","source":"Crossref","is-referenced-by-count":40,"title":["Economic analysis of endovascular interventions for femoropopliteal arterial disease: A systematic review and budget impact model for the United States and Germany"],"prefix":"10.1002","volume":"84","author":[{"given":"Jan B.","family":"Pietzsch","sequence":"first","affiliation":[{"name":"Wing Tech Inc. Menlo Park California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1704-6067","authenticated-orcid":false,"given":"Benjamin P.","family":"Geisler","sequence":"additional","affiliation":[{"name":"Wing Tech Inc. Menlo Park California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abigail M.","family":"Garner","sequence":"additional","affiliation":[{"name":"Wing Tech Inc. Menlo Park California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Zeller","sequence":"additional","affiliation":[{"name":"Universit\u00e4ts\u2010Herzzentrums Freiburg \u2022 Bad Krozingen Bad Krozingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael R.","family":"Jaff","sequence":"additional","affiliation":[{"name":"Massachusetts General Hospital Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,5,27]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.05.099"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.003954"},{"key":"e_1_2_5_4_1","unstructured":"LehmacherW.Kompetenzfeld \u201cPeripheres arterielles Verschlussleiden (pAVK)\u201d2012Available from:http:\/\/imsieweb.uni\u2010koeln.de\/lehre\/kompetenzfelder\/pavk\/pavk.pdf. 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