{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T19:56:36Z","timestamp":1760298996093},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,3,19]],"date-time":"2015-03-19T00:00:00Z","timestamp":1426723200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Postprocedural paravalvular leak (PVL)\u2009\u2265\u20092 has been shown to be associated with worse outcomes after transcatheter aortic valve implantation (TAVI). This study sought to identify predictive factors of postprocedural PVL\u2009\u2265\u20092 after TAVI with the Edwards valve.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>A total of 176 patients with Edwards TAVI (aged 83.4\u2009\u00b1\u20097.4 years, Logistic EuroSCORE [the Logistic European System for Cardiac Operative Risk Evaluation] 18.8\u2009\u00b1\u200912.0, transfemoral 54.5%) who had preprocedural multidetector computed tomography (MDCT) were studied. A PVL\u2009\u2265\u20092 was observed in 12.5% of cases. By multivariate analysis, only the valve calcification index (VCI) defined as aortic root calcification volume\/body surface area (odds ratio [OR]\u2009=\u20091.002, 95% confidence interval [CI]\u2009=\u20091.001\u20131.004, <jats:italic>P<\/jats:italic>\u2009=\u20090.006) and the valve diameter\/the calculated average annulus diameter (CAAD) by MDCT (OR\u2009=\u20090.683, 95% CI\u2009=\u20090.474\u20130.984, <jats:italic>P<\/jats:italic>\u2009=\u20090.041) were identified as independent predictors of postprocedural PVL\u2009\u2265\u20092. A score predicting postprocedural PVL\u2009\u2265\u20092 (PVL score) was determined by allotting one point when the valve diameter\/CAAD ratio was &lt;1.055 and one point when VCI was &gt;418.4 mm<jats:sup>3<\/jats:sup>\/m<jats:sup>2<\/jats:sup>, and summing all points accrued. Area under receiver\u2010operator characteristic curves of PVL score was 0.71 (95% CI\u2009=\u20090.59\u20130.83, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). The incidence of PVL\u2009\u2265\u20092 was 5.3% in patients with a PVL score of 0, 11.8% for a PVL score of 1 and 37.5% for a PVL score of 2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The only predictors of PVL\u2009\u2265\u20092 after Edwards valve implantation are the valve diameter\/CAAD and VCI. The PVL score could prove to be an excellent tool for predicting the risk of PVL. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.25665","type":"journal-article","created":{"date-parts":[[2014,9,10]],"date-time":"2014-09-10T00:45:26Z","timestamp":1410309926000},"page":"144-151","source":"Crossref","is-referenced-by-count":15,"title":["Can we predict postprocedural paravalvular leak after <scp>E<\/scp>dwards SAPIEN transcatheter aortic valve implantation?"],"prefix":"10.1002","volume":"86","author":[{"given":"Yusuke","family":"Watanabe","sequence":"first","affiliation":[{"name":"Institut Cardiovasculaire Paris Sud (ICPS), H\u00f4pital Priv\u00e9 Jacques Cartier, G\u00e9n\u00e9rale de Sant\u00e9 Massy France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thierry","family":"Lef\u00e8vre","sequence":"additional","affiliation":[{"name":"Institut Cardiovasculaire Paris Sud (ICPS), H\u00f4pital Priv\u00e9 Jacques Cartier, G\u00e9n\u00e9rale de 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