{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:08:52Z","timestamp":1762866532601},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,2,3]],"date-time":"2015-02-03T00:00:00Z","timestamp":1422921600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:p><jats:bold>Background<\/jats:bold>: Contemporary data regarding percutaneous closure of atrial septal defect\/patent foramen ovale (ASD\/PFO) are lacking. We evaluated the current trends in utilization of ASD\/PFO closure in adults and investigated the effect of annual hospital volume on in\u2010hospital outcomes. <jats:bold>Methods<\/jats:bold>: We queried the Nationwide Inpatient Sample between the years 2001 and 2010 using the <jats:italic>International Classification of Diseases<\/jats:italic> (ICD\u20109\u2010CM) procedure code for percutaneous closure of ASD\/PFO with device. Hierarchical mixed effects models were generated to identify the independent multivariate predictors of outcomes. <jats:bold>Results<\/jats:bold>: A total of 7,107 percutaneous ASD\/PFO closure procedures (weighted <jats:italic>n<\/jats:italic>\u2009=\u200934,992) were available for analysis. A 4.7\u2010fold increase in the utilization of this procedure from 3\/million in 2001 to 14\/million adults in 2010 in US (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) was noted. Overall, percutaneous ASD\/PFO closure was associated with 0.5% mortality and 12% in\u2010hospital complications. The utilization of intracardiac echocardiography (ICE) increased 15 fold (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) during the study period. The procedures performed at the high volume hospitals [2nd (14\u201337 procedures\/year) and 3rd (&gt;38 procedures\/year) tertile] were associated with significant reduction in complications, length of stay and cost of hospitalization when compared to those performed at lowest volume centers (&lt;13 procedures\/year). Majority (70.5%) of the studied hospitals were found to be performing &lt;10 procedures\/year hence deviating from the ACC\/AHA\/SCAI clinical competency guidelines. <jats:bold>Conclusions<\/jats:bold>: Low hospital volume is associated with an increased composite (mortality and procedural complications) adverse outcome following ASD\/PFO closure. In the interest of patient safety, implementation of the current guidelines for minimum required annual hospital volume to improve clinical outcomes is warranted. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/ccd.25794","type":"journal-article","created":{"date-parts":[[2014,12,22]],"date-time":"2014-12-22T13:41:45Z","timestamp":1419255705000},"page":"1073-1081","source":"Crossref","is-referenced-by-count":20,"title":["Influence of hospital volume on outcomes of percutaneous atrial septal defect and patent foramen ovale closure: A 10\u2010years us perspective"],"prefix":"10.1002","volume":"85","author":[{"given":"Vikas","family":"Singh","sequence":"first","affiliation":[{"name":"Cardiology University of Miami Miller School of Medicine Miami Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Apurva O.","family":"Badheka","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Yale School of Medicine New Haven Connecticut"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nileshkumar J.","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Staten Island University Hospital Staten Island New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ankit","family":"Chothani","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine MedStar Washington Hospital Center Washington District of Columbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathan","family":"Mehta","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine UPMC Shadyside Hospital Pittsburgh Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shilpkumar","family":"Arora","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Mt. 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