{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,8]],"date-time":"2023-10-08T11:13:13Z","timestamp":1696763593952},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,1,30]],"date-time":"2015-01-30T00:00:00Z","timestamp":1422576000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:p><jats:bold>Background<\/jats:bold>: To date, it remains unknown whether different types of new\u2010generation drug\u2010eluting stents have a differential impact on long\u2010term outcomes in diabetic patients. <jats:bold>Methods and Results<\/jats:bold>: In this historical cohort study (two Italian centers), we analyzed 400 diabetic patients with 553 coronary lesions treated with new\u2010generation CoCr zotarolimus\u2010eluting stents (R\u2010ZES: 136 patients, 196 lesions) or everolimus\u2010eluting stents (EES: 264 patients, 357 lesions) between October 2006 and August 2012. Primary endpoint was the occurrence of major adverse cardiac events (MACE) over a 2\u2010year follow\u2010up period. MACE was defined as all\u2010cause mortality, any myocardial infarction (MI) and\/or target lesion revascularization (TLR). Multivessel revascularization, intervention for restenotic lesion and use of intravascular ultrasound were significantly higher in the R\u2010ZES group, whereas small stent (\u22642.5 mm) deployment was significantly higher in the EES group. At 2\u2010year follow\u2010up, there was no significant difference in occurrence of MACE (R\u2010ZES vs EES: 22.8% vs 18.9%, <jats:italic>P<\/jats:italic>\u2009=\u20090.39). Similarly, no significant differences were observed in the composite endpoint of all\u2010cause mortality\/MI (10.0% vs 10.3%, <jats:italic>P<\/jats:italic>\u2009=\u20090.86) or TLR (12.4% vs 7.4%, <jats:italic>P<\/jats:italic>\u2009=\u20090.11). Adjustment for confounders and baseline propensity\u2010score matching did not alter the aforementioned associations. <jats:bold>Conclusion<\/jats:bold>: After 2 years of follow up similar outcomes (MACE, all\u2010cause mortality\/MI, TLR) were observed in real\u2010world diabetic patients, including those with complex lesions and patient characteristics, treated with R\u2010ZES and EES. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/ccd.25797","type":"journal-article","created":{"date-parts":[[2014,12,22]],"date-time":"2014-12-22T15:13:23Z","timestamp":1419261203000},"source":"Crossref","is-referenced-by-count":2,"title":["Comparison of 2\u2010year outcomes between zotarolimus\u2010eluting and everolimus\u2010eluting new\u2010generation cobalt\u2013chromium alloy stents in real\u2010world diabetic patients"],"prefix":"10.1002","volume":"86","author":[{"given":"Tadashi","family":"Miyazaki","sequence":"first","affiliation":[{"name":"Interventional Cardiology Unit, San Raffaele Scientific Institute Milan Italy"},{"name":"Interventional Cardiology Unit, EMO\u2010GVM Centro Cuore Columbus Milan Italy"},{"name":"Department of Cardiovascular Medicine Juntendo University Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azeem","family":"Latib","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit, San Raffaele Scientific Institute Milan Italy"},{"name":"Interventional Cardiology Unit, EMO\u2010GVM Centro Cuore Columbus Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasileios F.","family":"Panoulas","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit, San Raffaele Scientific Institute Milan Italy"},{"name":"Interventional Cardiology Unit, EMO\u2010GVM Centro Cuore Columbus Milan Italy"},{"name":"Physiology and Disease Prevention, National Heart and Lung Institute, Imperial College London London United 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