{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T22:33:00Z","timestamp":1781821980979,"version":"3.54.5"},"reference-count":19,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2015,2,3]],"date-time":"2015-02-03T00:00:00Z","timestamp":1422921600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The relationship between anemia, renal insufficiency, and the outcomes of TAVI patients has not been thoroughly studied. We aimed to evaluate the influence of pre\u2010 and post\u2010procedural anemia on the incidence of renal insufficiency, especially AKI, and on the outcomes of TAVI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data from the French national TAVI registry were collected in 3,472 patients who underwent TAVI between January 2010 and December 2012. Of these 2,137 were in the no\/mild anemia group, 748 were in the moderate anemia group, and 587 were in the severe anemia group before TAVI. Furthermore, we divided the 3,472 patients into three groups according to post\u2010procedural anemia, measured as post\u2010procedural hemoglobin (Hb) drop: &lt;2 g\/dl (<jats:italic>n<\/jats:italic>\u2009=\u20091,633, group 1), 2 to &lt;4 g\/dl (<jats:italic>n<\/jats:italic>\u2009=\u20091,458, group 2), and &gt;4 g\/dl (<jats:italic>n<\/jats:italic>\u2009=\u2009381, group 3). Procedure and outcome variables were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Increased severity of anemia before TAVI was associated with significantly different rates of 1\u2010year mortality (15%, 19%, and 24%, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01), with similar differences in the incidence of AKI (5%, 8%, and 10%, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). Increased severity of Hb drop was associated with significantly different rates of 1\u2010year mortality (16%, 18%, and 23%, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01), and with similar differences in the incidence of AKI (6%, 7%, and 10%, <jats:italic>P<\/jats:italic>\u2009=\u20090.04). Both pre\u2010 and post\u2010procedural anemia were predictors of the incidence of AKI (OR 1.82, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01; OR 1.82, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01, respectively) and 1\u2010year mortality (HR 1.44, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01; HR 1.50, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Both pre\u2010 and post\u2010procedural anemia were significantly associated AKI and 1\u2010year mortality. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.25832","type":"journal-article","created":{"date-parts":[[2015,1,13]],"date-time":"2015-01-13T15:49:32Z","timestamp":1421164172000},"page":"1231-1239","source":"Crossref","is-referenced-by-count":41,"title":["Impact of pre\u2010 and post\u2010procedural anemia on the incidence of acute kidney injury and 1\u2010year mortality in patients undergoing transcatheter aortic valve implantation (from the <scp>F<\/scp>rench <scp>A<\/scp>ortic <scp>N<\/scp>ational <scp>C<\/scp>ore<scp>V<\/scp>alve and <scp>E<\/scp>dwards 2 [<scp>FRANCE<\/scp> 2] <scp>R<\/scp>egistry)"],"prefix":"10.1002","volume":"85","author":[{"given":"Takahide","family":"Arai","sequence":"first","affiliation":[{"name":"Department of Cardiology Institut Cardiovasculaire Paris Sud Massy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie\u2010Claude","family":"Morice","sequence":"additional","affiliation":[{"name":"Department of Cardiology Institut Cardiovasculaire Paris Sud Massy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen A.","family":"O'Connor","sequence":"additional","affiliation":[{"name":"Department of Cardiology Institut Cardiovasculaire Paris Sud Massy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanori","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Cardiology Centre Hospitalier Universitaire Henri Mondor Creteil France"},{"name":"Department of Cardiology Toyohashi Heart Center Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9l\u00e8ne","family":"Eltchaninoff","sequence":"additional","affiliation":[{"name":"Department of Cardiology CHU Rouen Rouen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Leguerrier","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery CHU Rennes Rennes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Leprince","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery CHU Pitie\u2010Salp\u00e9tri\u00e8re Paris 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