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In this way, the model accounted for the mechanical response not only of the arterial wall, but also of the surrounding tissue. Four stents (2 balloon\u2010expandable including prestenting and 2 self\u2010expandable) were virtually implanted and the stent final configuration, anchoring, migration forces, arterial wall stresses, paravalvular regurgitation, and device mechanical performance were evaluated. A Sapien29 device with prestenting was indicated as the optimal approach for this specific patient as it had a fully open valve, safe anchoring along the entire circumference, low risk of paravalvular leak, and arterial rupture. However, at the time of the PPVI procedure, after balloon sizing, device implantation was suspended due to perceived high risk of device embolization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>FE analysis allows a comparison between different treatment scenarios to add information to the clinical decision making process. However, further studies are required to fully predict patient\u2010specific response to stenting and therefore true clinical outcomes. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.25944","type":"journal-article","created":{"date-parts":[[2015,4,9]],"date-time":"2015-04-09T09:24:09Z","timestamp":1428571449000},"page":"1120-1130","source":"Crossref","is-referenced-by-count":20,"title":["Patient\u2010specific finite element models to support clinical decisions: A lesson learnt from a case study of percutaneous pulmonary valve implantation"],"prefix":"10.1002","volume":"86","author":[{"given":"Giorgia M.","family":"Bosi","sequence":"first","affiliation":[{"name":"UCL Institute of Cardiovascular Science &amp; Great Ormond Street Hospital for Children London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio","family":"Capelli","sequence":"additional","affiliation":[{"name":"UCL Institute of Cardiovascular Science &amp; Great Ormond Street Hospital for Children London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sachin","family":"Khambadkone","sequence":"additional","affiliation":[{"name":"UCL Institute of Cardiovascular Science &amp; Great Ormond Street Hospital for Children London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew M.","family":"Taylor","sequence":"additional","affiliation":[{"name":"UCL Institute of Cardiovascular Science &amp; Great Ormond Street Hospital for Children London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Schievano","sequence":"additional","affiliation":[{"name":"UCL Institute of Cardiovascular Science &amp; Great Ormond Street Hospital for Children London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,4,9]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ppedcard.2012.02.007"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.735779"},{"key":"e_1_2_7_4_1","unstructured":"Guidance for industry and FDA staff. 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