{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T03:36:54Z","timestamp":1762659414457},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,5,23]],"date-time":"2015-05-23T00:00:00Z","timestamp":1432339200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the rate of Vascular complications in steroid treated patients undergoing transfemoral aortic valve implantation (TAVI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Steroid therapy has been associated with increased post\u2010surgical bleeding. Vascular complications are a major concern in patients undergoing TAVI. However, the effect of corticosteroids on vascular complications has not been assessed in these patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a retrospective analysis of 220 consecutive patients undergoing transfemoral TAVI at our institute between 2009 and 2013. Patients who were on steroids at the time of the procedure (<jats:italic>n<\/jats:italic>\u2009=\u200925) were compared with those who were not (<jats:italic>n<\/jats:italic>\u2009=\u2009195).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Baseline characteristics between groups were similar except for greater incidence of chronic renal failure (52 vs. 25%, <jats:italic>P<\/jats:italic>\u2009=\u20090.05) and lower left ventricular ejection fraction (50.3 vs. 55.8%, <jats:italic>P<\/jats:italic>\u2009=\u20090.037) in the steroid group. The rate of procedural success and nonvascular complication were similar in both groups with the exception of more temporary AV block in the steroid group (24 vs. 8%, <jats:italic>P<\/jats:italic>\u2009=\u20090.016). Patients treated with steroids had significantly more minor vascular complication (44 vs. 23%, <jats:italic>P<\/jats:italic>\u2009=\u20090.024), and significantly more femoral artery stenosis (16 vs. 5%, <jats:italic>P<\/jats:italic>\u2009=\u20090.036), occlusion (8 vs. 1%, <jats:italic>P<\/jats:italic>\u2009=\u20090.014), need for femoral artery percutaneous transluminal angioplasty (PTA) (32 vs. 12%, <jats:italic>P<\/jats:italic>\u2009=\u20090.009), and femoral artery PTA or stenting (32% vs. 15%, <jats:italic>P<\/jats:italic>\u2009=\u20090.031). On multivariate analysis steroid treatment was the only predictor of minor vascular complications (RR=2.65, 95% CI 1.04\u20106.8, <jats:italic>P<\/jats:italic>\u2009=\u20090.042).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Concurrent corticosteroid treatment is associated with a higher rate of minor vascular complication following transfemoral TAVI. Operators should be aware of this risk when assessing patients for the procedure. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.26014","type":"journal-article","created":{"date-parts":[[2015,5,23]],"date-time":"2015-05-23T08:16:47Z","timestamp":1432369007000},"page":"341-346","source":"Crossref","is-referenced-by-count":11,"title":["Vascular complications in steroid treated patients undergoing transfemoral aortic valve 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