{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T15:18:56Z","timestamp":1768317536801,"version":"3.49.0"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,11,6]],"date-time":"2015-11-06T00:00:00Z","timestamp":1446768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"The Scientific and Technological Research Council of Turkey (TUBITAK)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The use of covered stent grafts during percutaneous coronary intervention (PCI) is a life saving solution to seal acute iatrogenic vessel rupture. However, the presence of an impenetrable mechanical barrier is also appealing during treatment of friable coronary plaques but the synthetic PTFE\u2010membrane that might trigger excessive neointimal proliferation has limited its elective\u2010use. Pericardium tissue may offer an appealing \u201cnatural\u201d alternative. Aim of our study is to report the consecutive 5\u2010year single center experience with the use of pericardium\u2010covered stents (PCS) (ITGI\u2010Medical, Israel) in a variety of emergency and elective applications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Nineteen consecutive patients undergoing implantation of PCS at the Royal Brompton in the last 5\u2010years. Reasons for PCS implantation included treatment of degenerated vein grafts, large coronary aneurysms, and acute iatrogenic vessel rupture.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Angiographic success, defined as the ability of the device to be deployed in the indexed lesion with no contrast extravasation with residual angiographic stenosis &lt;30% and a final thrombolysis in myocardial infarction (TIMI)\u20103 flow was achieved in all cases. Procedural success, defined as the achievement of angiographic success without any major adverse cardiovascular event (MACE) was achieved in 94.7% of patients. In\u2010stent restenosis (ISR) was observed in 26.3% and all patients underwent successful target vessel revascularization with DES (mean time to restenosis 9.0\u2009\u00b1\u20094.0 months). At a mean follow\u2010up of 32.5\u2009\u00b1\u200923.3 months no acute or late stent thrombosis was observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>PCSs were effective in the treatment of friable embolization\u2010prone coronary plaques, sealing of acute iatrogenic vessel rupture and exclusion of large aneurysms with no thrombosis but high target lesion revascularization. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.26131","type":"journal-article","created":{"date-parts":[[2015,11,6]],"date-time":"2015-11-06T10:49:40Z","timestamp":1446806980000},"page":"712-719","source":"Crossref","is-referenced-by-count":17,"title":["Indications and immediate and long\u2010term results of a novel pericardium covered stent graft: Consecutive 5 year single center experience"],"prefix":"10.1002","volume":"87","author":[{"given":"Gioel Gabrio","family":"Secco","sequence":"first","affiliation":[{"name":"NIHR Biomedical Research Unit Royal Brompton &amp; 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