{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T17:41:24Z","timestamp":1762623684535},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,9,2]],"date-time":"2015-09-02T00:00:00Z","timestamp":1441152000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Aim of this observational study was to analyze today's real\u2010life treatment strategies in elderly patients with an acute myocardial infarction (AMI) and to assess the association between 28\u2010day\u2010case fatality and invasive strategy (percutaneous coronary intervention\/coronary artery bypass grafting).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Elderly patients increasingly constitute a large proportion of the AMI population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The present study is an analysis of all patients aged 75\u201384 years, who were enrolled in the German population\u2010based MONICA\/KORA MI registry between 2009 and 2012 and who were defined as nonfatal at least 24 hours surviving AMI cases according to MONICA definition. Multivariable logistic regression analyses were conducted for the total study population and stratified by type of AMI (ST\u2010segment elevation MI [STEMI], Non\u2010ST\u2010segment elevation MI [NSTEMI], and bundle branch block [BBB]).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Out of the 1,191 elderlies, 61.9% were treated invasively. In the multivariable analysis, the odds ratio (OR) for 28\u2010day\u2010case fatality in patients treated with invasive versus conservative strategy was 0.43 (95% CI 0.27\u20130.69). Stratified analyses revealed an OR of 0.27 (95% CI 0.13\u20130.56) for patients with NSTEMI. In patients with STEMI or BBB also a positive trend for invasive strategy was observed (OR 0.40; 95% CI 0.13\u20131.27 and OR 0.76; 95% CI 0.16\u20133.66, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Invasive revascularization therapy was independently associated with short\u2010term survival in elderly patients, particularly in those with NSTEMI. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.26159","type":"journal-article","created":{"date-parts":[[2015,9,2]],"date-time":"2015-09-02T21:52:51Z","timestamp":1441230771000},"page":"680-688","source":"Crossref","is-referenced-by-count":8,"title":["Acute myocardial infarction in the elderly: Treatment strategies and 28\u2010day\u2010case fatality from the <scp>MONICA\/KORA<\/scp> myocardial infarction registry"],"prefix":"10.1002","volume":"87","author":[{"given":"Ute","family":"Amann","sequence":"first","affiliation":[{"name":"MONICA\/KORA Myocardial Infarction Registry, Central Hospital of Augsburg Augsburg Germany"},{"name":"Institute of Epidemiology II, Helmholtz Zentrum M\u00fcnchen, German Research Center for Environmental Health (GmbH) Neuherberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inge","family":"Kirchberger","sequence":"additional","affiliation":[{"name":"MONICA\/KORA Myocardial Infarction Registry, Central Hospital of Augsburg Augsburg Germany"},{"name":"Institute of Epidemiology II, Helmholtz Zentrum M\u00fcnchen, German Research Center for Environmental Health (GmbH) Neuherberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margit","family":"Heier","sequence":"additional","affiliation":[{"name":"MONICA\/KORA Myocardial Infarction Registry, Central Hospital of Augsburg Augsburg Germany"},{"name":"Institute of Epidemiology II, Helmholtz Zentrum M\u00fcnchen, German Research Center for Environmental Health (GmbH) Neuherberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"von Scheidt","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I\u2010Cardiology Central Hospital of Augsburg Augsburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernhard","family":"Kuch","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I\u2010Cardiology Central Hospital of Augsburg Augsburg Germany"},{"name":"Department of Internal Medicine\/Cardiology Hospital of N\u00f6rdlingen N\u00f6rdlingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annette","family":"Peters","sequence":"additional","affiliation":[{"name":"Institute of Epidemiology II, Helmholtz Zentrum M\u00fcnchen, German Research Center for Environmental Health (GmbH) Neuherberg 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