{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T17:55:31Z","timestamp":1780077331810,"version":"3.54.0"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,10,20]],"date-time":"2015-10-20T00:00:00Z","timestamp":1445299200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Embolic protection devices (EPDs) have been designed and introduced to reduce distal embolization and peri\u2010procedural myocardial infarction during saphenous vein graft (SVG) intervention. Current guidelines give a class I recommendation to EPD use during SVG intervention when technically feasible. However, the routine use of these devices has recently been debated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analyzed 1,359 patients undergoing isolated SVG intervention between 2008 and 2013 in the British Columbia Cardiac Registry. We analyzed (a) post\u2010procedural TIMI flow; and (b) target vessel revascularization (TVR) and mortality at 1 and 2 years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>EPD use was an independent predictor of post\u2010procedural TIMI 2\/3 flow (OR\u2009=\u20092.38, 95% CI: 1.51\u20133.74, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). At 1 year, EPD use was an independent predictor for lower TVR (HR\u2009=\u20090.35, 95% CI: 0.14\u20130.85, <jats:italic>P<\/jats:italic>\u2009=\u20090.021) and a trend towards lower mortality (HR\u2009=\u20090.45, 95% CI: 0.18\u20131.10, <jats:italic>P<\/jats:italic>\u2009=\u20090.082). These associations were lost at 2 years where EPD use was not predictive of mortality (HR\u2009=\u20090.62, 95% CI: 0.33\u20131.17, <jats:italic>P<\/jats:italic>\u2009=\u20090.144) or TVR (HR\u2009=\u20090.70, 95% CI: 0.41\u20131.17, <jats:italic>P<\/jats:italic>\u2009=\u20090.176). These findings were confirmed in propensity\u2010matched and inverse probability treatment weighted analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this analysis of patients undergoing SVG intervention, EPD use was a strong predictor for improved post\u2010procedural TIMI flow. Whilst EPD use was associated with lower TVR and a trend for lower mortality at 1 year, these associations were lost at 2 years. These findings would appear to support the use of EPD for SVG intervention. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.26237","type":"journal-article","created":{"date-parts":[[2015,10,20]],"date-time":"2015-10-20T16:42:55Z","timestamp":1445359375000},"page":"73-83","source":"Crossref","is-referenced-by-count":12,"title":["Embolic protection device use and its association with procedural safety and long\u2010term outcomes following saphenous vein graft intervention: An analysis from the British Columbia Cardiac registry"],"prefix":"10.1002","volume":"88","author":[{"given":"M. Bilal","family":"Iqbal","sequence":"first","affiliation":[{"name":"Victoria Heart Institute Foundation Victoria British Columbia Canada"},{"name":"Royal Jubilee Hospital Victoria British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imad J.","family":"Nadra","sequence":"additional","affiliation":[{"name":"Victoria Heart Institute Foundation Victoria British Columbia Canada"},{"name":"Royal Jubilee Hospital Victoria British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lillian","family":"Ding","sequence":"additional","affiliation":[{"name":"Provincial Health Services Authority Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Fung","sequence":"additional","affiliation":[{"name":"Vancouver General Hospital Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eve","family":"Aymong","sequence":"additional","affiliation":[{"name":"St. Paul's Hospital Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert W.","family":"Chan","sequence":"additional","affiliation":[{"name":"Royal Columbian Hospital Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Hodge","sequence":"additional","affiliation":[{"name":"Kelowna General Hospital Kelowna British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Della Siega","sequence":"additional","affiliation":[{"name":"Victoria Heart Institute Foundation Victoria British Columbia Canada"},{"name":"Royal Jubilee Hospital Victoria British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon D.","family":"Robinson","sequence":"additional","affiliation":[{"name":"Victoria Heart Institute Foundation Victoria British Columbia Canada"},{"name":"Royal Jubilee Hospital Victoria British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the British Columbia Cardiac Registry 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