{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:44:26Z","timestamp":1743468266848},"reference-count":44,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,11,3]],"date-time":"2015-11-03T00:00:00Z","timestamp":1446508800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>A staged approach of percutaneous coronary intervention (PCI) followed by minimally invasive valve surgery (MIVS) is an alternative to the conventional combined coronary artery bypass and valve surgery for patients with concomitant coronary artery and valve disease. Limited data exist on degree of the completeness of revascularization achieved with this approach and its impact on outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 138 patients, who underwent a staged approach between January 2009 and June 2013, were retrospectively evaluated. Coronary angiograms were reviewed by two cardiologists blinded to outcomes and were then categorized into two groups: complete or incomplete revascularization, which was defined as \u22651 major epicardial coronary arteries of at least 2.0 mm diameter with \u226570% untreated obstruction after the index PCI and before MIVS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Complete and incomplete revascularization was achieved in 105 (76%) and 33 (24%) patients, respectively. The patients with incomplete revascularization had a lower ejection fraction, a higher STS score, and more prior myocardial infarctions and multi\u2010vessel coronary artery disease. There were no differences in the post\u2010operative complications, 30\u2010day mortality, or 3\u2010year survival (84 vs. 83%, <jats:italic>P<\/jats:italic>\u2009=\u20090.68). After a median follow\u2010up of 29 months, incompletely revascularized patients had a higher incidence of acute coronary syndrome (2.9 vs. 12.9%, <jats:italic>P<\/jats:italic>\u2009=\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In patients undergoing a staged approach of PCI followed by MIVS, incomplete revascularization did not significantly impact the short or mid\u2010term survival, but was associated with an increased incidence of acute coronary syndrome at follow\u2010up. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.26294","type":"journal-article","created":{"date-parts":[[2015,11,3]],"date-time":"2015-11-03T12:03:16Z","timestamp":1446552196000},"page":"329-337","source":"Crossref","is-referenced-by-count":6,"title":["Completeness of revascularization and its impact on the outcomes of a staged approach of percutaneous coronary intervention followed by minimally invasive valve surgery for patients with concomitant coronary artery and valvular heart disease"],"prefix":"10.1002","volume":"88","author":[{"given":"Andr\u00e9s M.","family":"Pineda","sequence":"first","affiliation":[{"name":"Columbia University Division of Cardiology at the Mount Sinai Heart Institute Miami Beach Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramesh","family":"Chandra","sequence":"additional","affiliation":[{"name":"Columbia University Division of Cardiology at the Mount Sinai Heart Institute Miami Beach Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saqib A.","family":"Gowani","sequence":"additional","affiliation":[{"name":"Columbia University Division of Cardiology at the Mount Sinai Heart Institute Miami Beach Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orlando","family":"Santana","sequence":"additional","affiliation":[{"name":"Columbia University Division of Cardiology at the Mount Sinai Heart Institute Miami Beach 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