{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T08:41:30Z","timestamp":1696668090436},"reference-count":5,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,2,26]],"date-time":"2016-02-26T00:00:00Z","timestamp":1456444800000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2016,2,15]]},"abstract":"<jats:title>Key Points<\/jats:title><jats:p>\n<jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>Mortality and bleeding risks after percutaneous coronary intervention (PCI) can be predicted with bedside models.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Bivalirudin reduces access and non\u2010access bleeding by almost half compared to heparin monotherapy and heparin with IIb\/IIIa use.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>In high (&gt;10%) baseline one\u2010year mortality risk PCI patients, bivalirudin reduces mortality by 4% compared to heparin with IIb\/IIIa therapy.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Increased acute stent thrombosis may be resolved with a 4\u2010hr post\u2010procedure bivalirudin infusion, eliminating bivalirudin's only major drawback except cost.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p>","DOI":"10.1002\/ccd.26441","type":"journal-article","created":{"date-parts":[[2016,2,27]],"date-time":"2016-02-27T11:43:43Z","timestamp":1456573423000},"page":"401-402","source":"Crossref","is-referenced-by-count":1,"title":["Risk\u2010guided use of the direct thrombin inhibitor bivalirudin"],"prefix":"10.1002","volume":"87","author":[{"given":"William B.","family":"Hillegass","sequence":"first","affiliation":[{"name":"Heart South Cardiovascular Group Alabaster Alabama"},{"name":"Department of Biostatistics University of Alabama at Birmingham Birmingham Alabama"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,26]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2011.02.011"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJY14M08_01"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0802944"},{"key":"e_1_2_2_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.2323"},{"key":"e_1_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.708"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.26441","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.26441","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T18:06:39Z","timestamp":1696615599000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.26441"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,15]]},"references-count":5,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,2,15]]}},"alternative-id":["10.1002\/ccd.26441"],"URL":"https:\/\/doi.org\/10.1002\/ccd.26441","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,15]]}}}