{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:32:20Z","timestamp":1761863540330},"reference-count":18,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,3,6]],"date-time":"2016-03-06T00:00:00Z","timestamp":1457222400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study was to assess the effect of a novel hourglass\u2010shaped balloon on reduction of paravalvular leak (PVL) in patients undergoing transcatheter aortic valve replacement (TAVR) with self\u2010expanding prostheses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>An important limitation of TAVR compared with surgical aortic valve replacement remains the higher incidence of PVL. A commonly used strategy to treat PVL is balloon postdilatation (BPD); however, the optimal technique for treating PVL after TAVR is unknown.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We examined consecutive patients with severe, symptomatic aortic stenosis who underwent TAVR with the Medtronic CoreValve followed by BPD with an InterValve V8 balloon for PVL grade \u22652+. Data from echocardiographic, multidetector computed tomographic, and angiographic images were reviewed. The primary endpoint was successful reduction in PVL to grade 1+ or less as assessed by intraprocedural echocardiography.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eleven patients were studied (median age, 82 years; 64% female). Ten patients (91%) demonstrated successful reduction in PVL after V8 BPD. In three patients, PVL was reduced to zero or trace. PVL remained unchanged in one patient (2+). Two patients had complete heart block associated with valve deployment and received permanent pacemakers. There were no occurrences of annular injury or major adverse clinical events.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>BPD with the V8 hourglass\u2010shaped balloon was feasible in reducing PVL from self\u2010expanding TAVR prostheses. \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.26462","type":"journal-article","created":{"date-parts":[[2016,3,6]],"date-time":"2016-03-06T11:48:43Z","timestamp":1457264923000},"page":"1306-1313","source":"Crossref","is-referenced-by-count":3,"title":["Initial findings using the V8 hourglass\u2010shaped valvuloplasty balloon for postdilatation in treating paravalvular leaks associated with transcatheter self\u2010expanding aortic valve prosthesis"],"prefix":"10.1002","volume":"87","author":[{"given":"Azeem","family":"Latib","sequence":"first","affiliation":[{"name":"Interventional Cardiology Unit, San Raffaele Scientific Institute and EMO\u2010GVM Centro Cuore Columbus Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wesley","family":"Pedersen","sequence":"additional","affiliation":[{"name":"Center for Valve and Structural Heart Disease, Minneapolis Heart Institute Foundation, Abbott Northwestern Hospital Minneapolis Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Maisano","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Universit\u00e4tsSpital Z\u00fcrich Z\u00fcrich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Lesser","sequence":"additional","affiliation":[{"name":"Center for Valve and Structural Heart Disease, Minneapolis Heart Institute Foundation, Abbott Northwestern Hospital Minneapolis Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neil","family":"Ruparelia","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit, San Raffaele Scientific Institute and EMO\u2010GVM Centro Cuore Columbus Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filippo","family":"Figini","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit, San Raffaele Scientific Institute and EMO\u2010GVM Centro Cuore Columbus Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Colombo","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit, San Raffaele Scientific Institute and EMO\u2010GVM Centro Cuore Columbus Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anil","family":"Poulose","sequence":"additional","affiliation":[{"name":"Center for Valve and Structural Heart Disease, Minneapolis Heart Institute Foundation, Abbott Northwestern Hospital Minneapolis Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Kolbeck","sequence":"additional","affiliation":[{"name":"Center for Valve and Structural Heart Disease, Minneapolis Heart Institute Foundation, Abbott Northwestern Hospital Minneapolis Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Mooney","sequence":"additional","affiliation":[{"name":"Center for Valve and Structural Heart Disease, Minneapolis Heart Institute Foundation, Abbott Northwestern Hospital Minneapolis Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Center for Valve and Structural Heart Disease, Minneapolis Heart Institute Foundation, Abbott Northwestern Hospital Minneapolis Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alicia","family":"Youssef","sequence":"additional","affiliation":[{"name":"Center for Valve and Structural Heart Disease, Minneapolis Heart Institute Foundation, Abbott Northwestern Hospital Minneapolis Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Ungs","sequence":"additional","affiliation":[{"name":"Center for Valve and Structural Heart Disease, Minneapolis Heart Institute Foundation, Abbott Northwestern Hospital Minneapolis Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irv","family":"Goldenberg","sequence":"additional","affiliation":[{"name":"Twin Cities Heart Foundation Minneapolis Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Sorajja","sequence":"additional","affiliation":[{"name":"Center for Valve and Structural Heart Disease, Minneapolis Heart Institute Foundation, Abbott Northwestern Hospital Minneapolis 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