{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T07:40:42Z","timestamp":1695973242077},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,5,3]],"date-time":"2016-05-03T00:00:00Z","timestamp":1462233600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:p>Bioprosthesis degeneration is a relevant clinical issue that is increasingly developing with the higher expectancy of life. Its treatment may be further complicated by the presence of paravalvular leaks, which are usually consequence of tissue friability, annular calcification, and infection. The surgical treatment of such complex conditions may be too risky, so percutaneous techniques in selected centers are becoming an attracting option. We report the case of a 65\u2010year\u2010old gentleman with a previous aortic valve replacement (Perimount n.25) who was admitted with worsening heart failure and transoesophageal evidence of severe intraprosthetic regurgitation and a large paravalvular leak. Since he was judged at too high risk for surgery, he was treated by a fully percutaneous approach. First, he had his large paravalvular leak closed by implantation of two plugs from both retrograde and anterograde routes (arterial\u2013venous loop created). After one month, he underwent a \u201cvalve\u2010in\u2010valve\u201d transcatheter aortic valve implantation with a fully repositionable Lotus 23 mm valve, which was able to restore a completely normal aortic valve function and let to a dramatic improvement of his functional status at 6\u2010month follow\u2010up (from NYHA IV to NYHA I), when a transthoracic echocardiogram also confirmed the absence of any aortic regurgitation. This case shows how a tailored step\u2010by\u2010step fully percutaneous strategy is safe and feasible in high\u2010risk patients with both bioprosthesis degeneration and large paravalvular leaks. This novel opportunity would need to be better evaluated in properly addressed long\u2010term clinical studies. \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/ccd.26552","type":"journal-article","created":{"date-parts":[[2016,5,4]],"date-time":"2016-05-04T14:00:24Z","timestamp":1462370424000},"page":"169-174","source":"Crossref","is-referenced-by-count":2,"title":["Successful percutaneous paravalvular leak closure followed by transfemoral aortic lotus valve\u2010in\u2010valve implantation in a degenerated surgical bioprosthesis"],"prefix":"10.1002","volume":"91","author":[{"given":"Roberto","family":"Nerla","sequence":"first","affiliation":[{"name":"Interventional Cardiology Unit GVM Maria Cecilia Hospital Cotignola Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Cremonesi","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit GVM Maria Cecilia Hospital Cotignola Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fausto","family":"Castriota","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit GVM Maria Cecilia Hospital Cotignola Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,5,3]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00834-2"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2015.08.012"},{"key":"e_1_2_5_4_1","article-title":"First Lotus aortic valve\u2010in\u2010valve implantation to treat degenerated Mitroflow bioprostheses","volume":"11","author":"Castriota F","year":"2015","journal-title":"Eurointervention"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1067\/mtc.2001.116470"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2011.11.007"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2008.08.071"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2010.12.053"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.104505"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.03.074"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2004.06.033"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.25992"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2013.10.012"},{"key":"e_1_2_5_14_1","first-page":"e57","article-title":"American College of Cardiology\/American Heart Association Task Force on Practice Guidelines. 2014 AHA\/ACC guideline for the management of patients with valvular heart disease: A report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines","volume":"63","author":"RA Nishimura","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"e_1_2_5_15_1","first-page":"2019","article-title":"Transcatheter valve\u2010in\u2010valve and valve\u2010in\u2010ring for treating aortic and mitral surgical prosthetic dysfunction","volume":"66","author":"Paradis JM","year":"2015","journal-title":"JACC Cardiovasc Interv"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.7246"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.26552","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.26552","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.26552","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T14:18:15Z","timestamp":1695910695000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.26552"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,3]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["10.1002\/ccd.26552"],"URL":"https:\/\/doi.org\/10.1002\/ccd.26552","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5,3]]}}}