{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T22:02:08Z","timestamp":1761948128300},"reference-count":13,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T00:00:00Z","timestamp":1463443200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2016,11,15]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To report procedural and 30\u2010day outcomes following percutaneous transcatheter valve\u2010in\u2010valve (VIV) implantation for tricuspid bioprosthesis failure, with a new generation balloon\u2010expandable transcatheter aortic valve implantation prosthesis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Severe tricuspid regurgitation is associated with a reduction in survival and increased morbidity. Many patients previously treated with tricuspid valve replacement require further intervention due to bioprosthesis failure. Surgical redo is the \u201cgold standard\u201d treatment however this is technically challenging and associated with significant risk. Percutaneous VIV intervention that is now well established in the management of aortic and mitral bioprosthesis failure may therefore be an alternative treatment option.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study population consisted of all patients that underwent percutaneous transcatheter tricuspid VIV implantation for tricuspid bioprosthesis failure at the San Raffaele Scientific Institute, Milan, Italy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Five patients underwent successful transfemoral transcatheter tricuspid VIV implantation for bioprosthetic failure. One patient suffered acute kidney injury that was successfully medically managed. The remaining patients suffered no complications prior to hospital discharge. During 30\u2010day follow\u2010up, all patients reported a significant improvement in their functional status with normal valve function. Additionally, we observed an improvement in renal function (eGFR baseline 62.0\u2009\u00b1\u200916.5 vs. follow\u2010up 70.2\u2009\u00b1\u200923.1 ml\/min\/m<jats:sup>2<\/jats:sup>, <jats:italic>P<\/jats:italic>\u2009=\u20090.12) and improved hepatic congestion: bilirubin (1.47\u2009\u00b1\u20090.8 vs. 1.01\u2009\u00b1\u20090.7 mg\/DL, <jats:italic>P<\/jats:italic>\u2009=\u20090.12), alanine aminotransferase (31.0\u2009\u00b1\u200911.1 vs. 23.2\u2009\u00b1\u20095.1 U\/L, <jats:italic>P<\/jats:italic>\u2009=\u20090.11) and aspartate aminotransferase (35.8\u2009\u00b1\u20096.3 vs. 29.8\u2009\u00b1\u200913.6 U\/L, <jats:italic>P<\/jats:italic>\u2009=\u20090.12).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Transfemoral, transcatheter VIV treatment with a new generation balloon expandable devices appears to be a safe and efficacious treatment option for tricuspid bioprosthesis failure. \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.26584","type":"journal-article","created":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T06:48:27Z","timestamp":1463467707000},"page":"994-1001","source":"Crossref","is-referenced-by-count":10,"title":["Percutaneous Transcatheter Treatment for Tricuspid Bioprosthesis Failure"],"prefix":"10.1002","volume":"88","author":[{"given":"Neil","family":"Ruparelia","sequence":"first","affiliation":[{"name":"Department of Interventional Cardiology San Raffaele Scientific Institute Milan Italy"},{"name":"Department of Cardiology Imperial College London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Mangieri","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology San Raffaele Scientific Institute Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Ancona","sequence":"additional","affiliation":[{"name":"Department of 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