{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T22:07:48Z","timestamp":1791410868348,"version":"4.3.3"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,6,3]],"date-time":"2016-06-03T00:00:00Z","timestamp":1464912000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To identify factors associated with outcomes following rotational atherectomy (RA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>RA is an effective way to mechanically modify heavily calcified lesions before stenting; however its outcomes are not well defined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>Retrospective evaluation of all patients who underwent RA in three large UK centers (Leeds General Infirmary (LGI), Royal Infirmary of Edinburgh (RIE) and University Hospital of North Staffordshire (UHNS)) from March 2005 to January 2013. Five hundred and eighteen patients had RA with median follow\u2010up period of 22 months. About 68.3% were male, 28.7% had DM and 34.6% were treated because of ACS. Stents were deployed in 97.3% of the patients while 30.7% of the procedures were performed transradially. Maximum burr was \u22641.75 mm in 85.5% and the mean SYNTAX score was 19.5\u2009\u00b1\u200911.6. Peri\u2010procedural complications occurred in 6.4% and vascular access complications in 1.9%. Outcomes in the follow\u2010up period were: MACE 17.8%, cardiac death 7.1%, MI 11.7%, TVR 7.5%, all\u2010cause death 13.7%, definite stent thrombosis (ST) 1.4% and stroke 2.9%. Patients with intermediate and high SYNTAX scores were more likely to suffer MACE, cardiac death, MI, all\u2010cause death and ST. Patients with a SYNTAX score &gt;32 were also more likely to have a peri\u2010procedural complication. Multiple logistic regression analysis showed that the presence of PVD (<jats:italic>P<\/jats:italic>\u2009=\u20090.026, OR\u2009=\u20092.0), DM (<jats:italic>P<\/jats:italic>\u2009=\u20090.008, OR\u2009=\u20092.1), ACS presentation (<jats:italic>P<\/jats:italic>\u2009=\u20090.011, OR\u2009=\u20092.1) and SYNTAX score \u226523 (<jats:italic>P<\/jats:italic>\u2009=\u20090.02, OR\u2009=\u20091.9) had a significant association with MACE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>RA is safe and effective, with high rate of procedural success and relatively low incidence of MACE. PVD, DM, ACS presentation and SYNTAX score were significant predictors for MACE. \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.26587","type":"journal-article","created":{"date-parts":[[2016,6,3]],"date-time":"2016-06-03T12:51:31Z","timestamp":1464958291000},"page":"546-553","source":"Crossref","is-referenced-by-count":26,"title":["Cardiovascular Outcomes Following Rotational Atherectomy: A UK Multicentre Experience"],"prefix":"10.1002","volume":"88","author":[{"given":"Christos","family":"Eftychiou","sequence":"first","affiliation":[{"name":"Department of Cardiology Leeds General Infirmary Leeds United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David S.","family":"Barmby","sequence":"additional","affiliation":[{"name":"Department of Cardiology Leeds General Infirmary Leeds United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon 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