{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:23:28Z","timestamp":1761578608359,"version":"3.37.3"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,10,3]],"date-time":"2016-10-03T00:00:00Z","timestamp":1475452800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:sec><jats:label\/><jats:p>We propose a mechanism of how stroke may be caused by thrombus aspiration during primary percutaneous coronary intervention (PPCI), and how it may be technique\u2010dependent.<\/jats:p><\/jats:sec><jats:sec><jats:label\/><jats:p>Two recent meta\u2010analyses report increased risk of stroke in patients undergoing routine thrombus aspiration during STEMI and the value of this technique has been controversial. The mechanism of stroke has not been fully explained.<\/jats:p><\/jats:sec><jats:sec><jats:label\/><jats:p>This case demonstrates 2 mechanisms by which aspiration might cause thrombus embolization.<\/jats:p><\/jats:sec><jats:sec><jats:label\/><jats:p>We recommend that if thrombus aspiration is performed during PPCI for STEMI, it should be done selectively and carefully. It is prudent to make sure the guide catheter tip is not free in the aorta when the aspiration catheter is withdrawn, to maintain suction on the aspiration catheter as it is withdrawn (particularly if the aspiration port seems to be obstructed), and to aspirate the guide catheter after the aspiration catheter is removed to capture any fragments of thrombus that remain in the guide catheter. \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.26682","type":"journal-article","created":{"date-parts":[[2016,10,11]],"date-time":"2016-10-11T13:21:09Z","timestamp":1476192069000},"page":"93-96","source":"Crossref","is-referenced-by-count":6,"title":["A mechanism for stroke complicating thrombus aspiration"],"prefix":"10.1002","volume":"89","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2211-5039","authenticated-orcid":false,"given":"Eddie D.","family":"Brown","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Geisinger Medical Center Danville Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James C.","family":"Blankenship","sequence":"additional","affiliation":[{"name":"Department of Cardiology Geisinger Medical Center Danville Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,10,3]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00448-1"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000433418"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.114.002258"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2014.11.021"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.04.025"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.25532"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1308789"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.115.001962"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2015.10.047"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2014.11.021"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2015.10.026"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60833-8"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0706416"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1160\/TH13-05-0433"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.25572"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-015-0846-z"},{"key":"e_1_2_4_18_1","first-page":"1","article-title":"Use and outcome of thrombus aspiration in patients with primary PCI for acute ST\u2010elevation myocardial infarction: Results from the multinational Euro Heart Survey PCI Registry","volume":"104","author":"Weipert KF","year":"2015","journal-title":"Heart Vessels"},{"key":"e_1_2_4_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.113.000964"},{"key":"e_1_2_4_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2015.09.010"},{"key":"e_1_2_4_21_1","first-page":"1236","article-title":"2015 focused update on primary PCI for patients with STEMI: an update of the 2011 ACCF\/AHA\/SCAI guideline for percutaneous coronary intervention and the 2013 ACCF\/AHA guideline for the management of ST\u2010elevation myocardial infarction: a report of the American College of Cardiology Foundation\/American Heart Association Task Force on Clinical Practice Guidelines and the Society for Cardiovascular Angiography and Interventions","volume":"67","author":"Levine GN","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"e_1_2_4_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2008.06.004"},{"key":"e_1_2_4_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2012.08.013"},{"key":"e_1_2_4_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv296"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.26682","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.26682","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.26682","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T19:59:07Z","timestamp":1695758347000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.26682"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,3]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1002\/ccd.26682"],"URL":"https:\/\/doi.org\/10.1002\/ccd.26682","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"type":"print","value":"1522-1946"},{"type":"electronic","value":"1522-726X"}],"subject":[],"published":{"date-parts":[[2016,10,3]]}}}