{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T12:59:30Z","timestamp":1772456370927,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,8,12]],"date-time":"2016-08-12T00:00:00Z","timestamp":1470960000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2017,2,15]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The objectives of the present study were to analyze the variation of renal function after transcatheter aortic valve replacement (TAVR) focused on acute kidney injury (AKI) and its impact on short\u2010 and mid\u2010term mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Changes on renal function after TAVR and their impact on clinical outcomes are incompletely understood until now.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>At two tertiary centers 221 consecutive patients were submitted to TAVR. Kidney injury was defined according to VARC\u20102 criteria. Patients were classified according to the presence (group 1) or absence (group 2) of AKI. Creatinine values were collected daily until seventh day after procedure, 1 month, 6 months, and then 1 year after TAVR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At baseline, groups were similar, except for EuroSCORE II (8.66% vs. 7.34%, <jats:italic>P<\/jats:italic>\u2009=\u20090.02) and glomerular filtration rate (GFR) (39.59 vs. 48.49 mL\/min.1.73 m<jats:sup>2<\/jats:sup>, <jats:italic>P<\/jats:italic>\u2009=\u20090.002). Overall 30 day\u2010mortality and 1\u2010year mortality were 6.3% and 14.0%, respectively. Both 30\u2010day mortality (23.1% vs. 1.2%, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and 1\u2010year mortality (44.2% vs. 4.7%, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) were higher in group 1. After multivariable\u2010adjusted models, the only independent predictor for AKI after TAVR was baseline GFR (HR: 1.37, 95% CI: 1.08\u20131.77, <jats:italic>P<\/jats:italic>\u2009=\u20090.01). The independent risk factors for 1\u2010year mortality were AKI (HR: 15.66, 95% CI: 6.07\u201344.63, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), COPD (HR: 3.14, 95% CI: 1.05\u20139.40, <jats:italic>P<\/jats:italic>\u2009=\u20090.04) and aortic regurgitation grade postprocedure\u2009\u2265\u20092 (<jats:italic>P<\/jats:italic>\u2009=\u20090.05) also after multivariate analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this TAVR cohort, baseline GFR was the only independent predictor of AKI, which negatively impacted on 30\u2010day and 1\u2010year mortality. \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.26693","type":"journal-article","created":{"date-parts":[[2016,8,12]],"date-time":"2016-08-12T07:19:05Z","timestamp":1470986345000},"page":"452-459","source":"Crossref","is-referenced-by-count":11,"title":["Prognostic value of renal function in patients with aortic stenosis treated with transcatheter aortic valve replacement"],"prefix":"10.1002","volume":"89","author":[{"given":"Rafael A.","family":"Meneguz\u2010Moreno","sequence":"first","affiliation":[{"name":"Instituto Dante Pazzanese de Cardiologia S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Auristela IO","family":"Ramos","sequence":"additional","affiliation":[{"name":"Instituto Dante Pazzanese de Cardiologia S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimytri","family":"Siqueira","sequence":"additional","affiliation":[{"name":"Instituto Dante Pazzanese de Cardiologia S\u00e3o Paulo Brazil"},{"name":"Hospital do Cora\u00e7\u00e3o S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"de Castro\u2010Filho","sequence":"additional","affiliation":[{"name":"Instituto Dante Pazzanese de Cardiologia S\u00e3o Paulo 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