{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T03:10:28Z","timestamp":1791947428508,"version":"4.3.4"},"reference-count":40,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2016,10,31]],"date-time":"2016-10-31T00:00:00Z","timestamp":1477872000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:p>The permanent metal prosthesis common to bare metal stents (BMS) as well as both first\u2010 and second\u2010generation drug\u2010eluting stents (DES) following treatment of coronary artery disease represents a long\u2010lasting substrate for late adverse coronary events including restenosis, thrombosis, and neoatherosclerosis. Following resorbtion, bioresorbable scaffolds (BRS) may eliminate this nidus and improve late outcomes through restoration of the vessel to more normal vascular structure and function. BRS represents a single platform which incorporates the mechanical features of metallic stents to provide safe and effective revascularization, suppression of restenosis and prevention of constrictive remodeling with long\u2010term restoration of the treated vessel to a more natural state. The landscape of BRS is rapidly evolving with new materials which target various performance goals for the duration of vascular support and polymer resorption time. The Absorb bioresorbable vascular scaffold (Absorb BVS), recently approved by United States Food and Drug Administration, has extensive clinical evidence to date in support of its clinical efficacy and safety. Recently published data from well\u2010executed randomized clinical trials (RCTs) as part of the ABSORB Clinical development program along with other investigator\u2010initiated trials provide insights into the safety and performance of this device in patients with de novo coronary lesions as well in the setting of ST\u2010segment elevation myocardial infarction (STEMI). This review provides a comprehensive, outcomes based understanding of the available evidence from RCTs that offer head\u2010to\u2010head comparisons of Absorb BVS with metallic everolimus\u2010eluting stents (EES). \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/ccd.26810","type":"journal-article","created":{"date-parts":[[2016,10,31]],"date-time":"2016-10-31T13:34:58Z","timestamp":1477920898000},"page":"21-30","source":"Crossref","is-referenced-by-count":9,"title":["Bioresorbable vascular scaffolds for the treatment of coronary artery disease: Clinical outcomes from randomized controlled trials"],"prefix":"10.1002","volume":"88","author":[{"given":"David G","family":"Rizik","sequence":"first","affiliation":[{"name":"Director of Structural and Coronary Intervention HonorHealth and the Scottsdale\u2010Lincoln Health Network Scottsdale Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James B","family":"Hermiller","sequence":"additional","affiliation":[{"name":"Director of Interventional Cardiology and Director of Interventional Cardiology Fellowship St. Vincent Heart Center of Indiana Indianapolis Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dean J.","family":"Kereiakes","sequence":"additional","affiliation":[{"name":"The Christ Hospital Heart and Vascular Center, The Lindner Research Center Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,10,31]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199408253310802"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(97)00334-3"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.94.6.1247"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.826479"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.097014"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2013.07.009"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.04.017"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1409312"},{"key":"e_1_2_3_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2015.03.028"},{"key":"e_1_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.12.036"},{"key":"e_1_2_3_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.03.042"},{"key":"e_1_2_3_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.001790"},{"key":"e_1_2_3_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2014.07.014"},{"key":"e_1_2_3_15_1","first-page":"357364","volume-title":"Coronary and Endovascular Stents, An Issue of Interventional Cardiology Clinics","author":"Capodanno D.","year":"2016"},{"key":"e_1_2_3_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2013.05.017"},{"key":"e_1_2_3_17_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV9I11A217"},{"key":"e_1_2_3_18_1","article-title":"The ABSORB EXTEND study: Preliminary report of the twelve\u2010month clinical outcomes in the first 512 patients enrolled","volume":"10","author":"Abizaid A","year":"2014","journal-title":"EuroIntervention"},{"key":"e_1_2_3_19_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jacc.2014.07.679","article-title":"ABSORB FIRST: An interim report on baseline characteristics and acute performance on the first 1,200 patients from a prospective, multi\u2010center, global registry","volume":"64","author":"Eeckhout E.","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"e_1_2_3_20_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJY14M07_11"},{"key":"e_1_2_3_21_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJY14M08_08"},{"key":"e_1_2_3_22_1","doi-asserted-by":"publisher","DOI":"10.5603\/KP.a2014.0147"},{"key":"e_1_2_3_23_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJY14M12_10"},{"key":"e_1_2_3_24_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV10I6A118"},{"key":"e_1_2_3_25_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV9I9A176"},{"key":"e_1_2_3_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht545"},{"key":"e_1_2_3_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-1235(15)30154-X"},{"key":"e_1_2_3_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.21136"},{"key":"e_1_2_3_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.22864"},{"key":"e_1_2_3_30_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV9I6A115"},{"key":"e_1_2_3_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61455-0"},{"key":"e_1_2_3_32_1","unstructured":"ChevalierB.The 2\u2010year clinical outcomes of the ABSORB II trial: First randomized comparison between the Absorb everolimus eluting bioresorbable vascular scaffold and the Xience everolimus eluting stent. 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