{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:49:25Z","timestamp":1761562165333},"reference-count":18,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2016,10,31]],"date-time":"2016-10-31T00:00:00Z","timestamp":1477872000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:p>First\u2010generation bioresorbable scaffolds (BRS), represented by the three marked\u2010approved devices (Absorb BVS 1.1, DESolve NX, and DREAMS) have demonstrated, in low to moderate angiographic scenarios, similar efficacy to current generation metallic drug\u2010eluting stents. However, a trend toward more device thrombosis have been observed, especially when the scaffolds are used in <jats:italic>off\u2010label<\/jats:italic> situations. Among the main shortcomings of this novel technology, we highlight: (1) Increased strut thickness (\u2265150 \u03bcm) and crossing profile; (2) low resistance to overexpansion; (3) lack of radiopacity, and; (4) special storage requirements. In order to overcome these limitations and improve their acute performance and midterm safety, a dozen of novel BRS are currently under research, in different stages of development. In the present review, we address three of these new technologies, pointing out their innovative features and initial clinical results. \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/ccd.26813","type":"journal-article","created":{"date-parts":[[2016,10,31]],"date-time":"2016-10-31T13:34:58Z","timestamp":1477920898000},"page":"54-59","source":"Crossref","is-referenced-by-count":3,"title":["The unmet needs: How future technologies will address current limitations of bioresorbable scaffold technology"],"prefix":"10.1002","volume":"88","author":[{"given":"Alexandre","family":"Abizaid","sequence":"first","affiliation":[{"name":"Instituto Dante Pazzanese de Cardiologia S\u00e3o Paulo Brazil"},{"name":"Hospital do Cora\u00e7\u00e3o \u2013 Associa\u00e7\u00e3o do Sanatorio S\u00edrio S\u00e3o Paulo Brazil"},{"name":"Hospital Israelita Albert Einstein S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"J.","family":"Ribamar Costa","sequence":"additional","affiliation":[{"name":"Instituto Dante Pazzanese de Cardiologia S\u00e3o Paulo Brazil"},{"name":"Hospital do Cora\u00e7\u00e3o \u2013 Associa\u00e7\u00e3o do Sanatorio S\u00edrio S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,10,31]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61455-0"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1509038"},{"key":"e_1_2_6_4_1","doi-asserted-by":"crossref","unstructured":"AbizaidA Ribamar CostaJJr BartorelliAL WhitbournR vanGeunsRJ ChevalierB PatelT SethA StutevilleM DorangeC CheongWF SudhirK SerruysPW.ABSORB EXTEND investigators. 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