{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:37:28Z","timestamp":1786977448466,"version":"build-2736575974"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,12,28]],"date-time":"2016-12-28T00:00:00Z","timestamp":1482883200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000046","name":"Abbott Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000046","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005035","name":"Biotronik","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005035","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:p>\n                    Aim. To determine the potential clinical impact of OCT (Optical Coherence Tomography) during primary percutaneous coronary intervention in patients presenting with ACS (Acute Coronary Syndrome). Methods and Results. FORMIDABLE is a multicentre retrospective registry enrolling all patients presenting with ACS and treated with an OCT\u2010guided approach, while the USZ registry enrolled patients treated with a standard angiography guided approach. Multivariate adjustment was performed via a propensity score matching. The number stents useds was the primary outcome, while the incidence of MACE (a composite of death, myocardial infarction, target vessel revascularization, and stent thrombosis) was the secondary endpoint. A total of 285 patients OCT\u2010guided and 1,547 angiography guided patients were enrolled, resulting in 270 for each cohort after propensity score with matching. Two stents were used in 12% versus 34%; 3 stents in 8% versus 38% of the patients (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.001). After a follow up of 700 days (450\u2013890), there was no difference in myocardial infarction (6% vs. 6%,\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.86), while MACE (11% vs. 16%,\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.06), target vessel revascularization (2% vs. 4%,\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.15) and stent thrombosis rates (0% vs. 2.7%,\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.26) were numerically lower for the OCT\u2010guided cohort but none of these endpoints did reach statistical significance. Conclusions. An OCT\u2010guided approach reduced the number of stents used, number of patients treated with more than one stent, while there was no statistically significant difference in clinical endpoints while most of them were numerically lower, including stent thrombosis rates. \u00a9 2016 Wiley Periodicals, Inc.\n                  <\/jats:p>","DOI":"10.1002\/ccd.26880","type":"journal-article","created":{"date-parts":[[2016,12,28]],"date-time":"2016-12-28T07:16:46Z","timestamp":1482909406000},"source":"Crossref","is-referenced-by-count":24,"title":["Impact of an optical coherence tomography guided approach in acute coronary syndromes: A propensity matched analysis from the international FORMIDABLE\u2010CARDIOGROUP IV and USZ registry"],"prefix":"10.1002","volume":"90","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0571-3918","authenticated-orcid":false,"given":"Mario","family":"Iannaccone","sequence":"first","affiliation":[{"name":"\u201cCitt\u00e0 della Scienza e della Salute,\u201d Department of Cardiology University of Turin Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"D'Ascenzo","sequence":"additional","affiliation":[{"name":"\u201cCitt\u00e0 della Scienza e della Salute,\u201d Department of Cardiology University of Turin Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio H.","family":"Frangieh","sequence":"additional","affiliation":[{"name":"Department of Cardiology Zurich University Hospital Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giampaolo","family":"Niccoli","sequence":"additional","affiliation":[{"name":"Division of Cardiology Institute of Cardiology, Catholic University of the Sacred Heart Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"Ugo","sequence":"additional","affiliation":[{"name":"Department of Cardiology \u201cS.G. Bosco Hospital,\u201d Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"Boccuzzi","sequence":"additional","affiliation":[{"name":"Department of Cardiology \u201cS.G. Bosco Hospital,\u201d Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Bertaina","sequence":"additional","affiliation":[{"name":"\u201cCitt\u00e0 della Scienza e della Salute,\u201d Department of Cardiology University of Turin Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Mancone","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular, Respiratory, Nephrologic, Anesthesiologic and Geriatric Sciences \u201cSapienza\u201d University of Rome Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Montefusco","sequence":"additional","affiliation":[{"name":"\u201cCitt\u00e0 della Scienza e della Salute,\u201d Department of Cardiology University of Turin Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Amabile","sequence":"additional","affiliation":[{"name":"Cardiology Department Institut Mutualiste Montsouris Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gennaro","family":"Sardella","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular, Respiratory, Nephrologic, Anesthesiologic and Geriatric Sciences \u201cSapienza\u201d University of Rome Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Motreff","sequence":"additional","affiliation":[{"name":"Cardiology Department, CHU Clermont\u2010Ferrand, Clermont\u2010Ferrand 63000, France Cardio Vascular Interventional Therapy and Imaging (CaVITI) UMR CNRS 6284, Auvergne University Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Toutouzas","sequence":"additional","affiliation":[{"name":"First Department of Cardiology Hippokration Hospital, Athens Medical School Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Colombo","sequence":"additional","affiliation":[{"name":"Department of Cardiology \u201cS.G. Bosco Hospital,\u201d Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Garbo","sequence":"additional","affiliation":[{"name":"Department of Cardiology \u201cS.G. Bosco Hospital,\u201d Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Biondi\u2010Zoccai","sequence":"additional","affiliation":[{"name":"Department of Medico\u2010Surgical Sciences and Biotechnologies Sapienza University of Rome, Latina, Italy; Department of AngioCardioNeurology, IRCCS Neuromed, Pozzilli, Italy and University Heart Center, Department of Cardiology, University Hospital Zurich  Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corrado","family":"Tamburino","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Cardio\u2010thoracic\u2010vascular Department Ferrarotto Hospital, University of Catania Catania Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierluigi","family":"Omed\u00e8","sequence":"additional","affiliation":[{"name":"\u201cCitt\u00e0 della Scienza e della Salute,\u201d Department of Cardiology University of Turin Turin 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