{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:36:05Z","timestamp":1786977365818,"version":"build-2736575974"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,1,21]],"date-time":"2017-01-21T00:00:00Z","timestamp":1484956800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To compare the long\u2010term clinical outcomes of paclitaxel drug\u2010coated\u2010balloons (DCB) and everolimus\u2010eluting\u2010stents (EES) following the treatment of de novo small vessel coronary artery disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>It is currently unclear whether treatment of de novo small vessel coronary disease with DCB is comparable to second generation drug\u2010eluting stents, which are the current standard of care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The present study enrolled 90 patients with small vessel coronary disease from the DCB treatment arm of the BELLO (Balloon Elution and Late Loss Optimization) trial and 2,000 patients treated with EES at the San Raffaele Scientific Institute. Propensity score matching was performed to adjust for differences in baseline clinical and angiographic characteristics, yielding a total of 181 patients: 90 patients with 94 lesions receiving DCB and 91 patients with 94 lesions receiving EES. Major adverse cardiac events (MACE) were defined as the composite of cardiac death, recurrent non\u2010fatal myocardial infarction, and target vessel revascularization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After propensity score matching, baseline clinical and angiographic characteristics were similar between the two groups. The cumulative MACE rate at 1\u2010year was 12.2% with DCB and 15.4% with EES (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.538). Patients in the DCB group had similar TLR rates as compared to EES over the same interval (4.4% vs. 5.6%;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.720). There were no cases of definite or probable stent or vessel thrombosis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The use of paclitaxel\u2010DCB appears to be associated with similar clinical outcomes when compared to second\u2010generation\u2010EES in small coronary artery disease. The findings of this study should be confirmed with larger prospective randomized studies with longer follow\u2010up. \u00a9 2017 Wiley Periodicals, Inc.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.26929","type":"journal-article","created":{"date-parts":[[2017,1,21]],"date-time":"2017-01-21T02:33:17Z","timestamp":1484965997000},"page":"380-386","source":"Crossref","is-referenced-by-count":18,"title":["A propensity score matched comparative study between paclitaxel\u2010coated balloon and everolimus\u2010eluting stents for the treatment of small coronary vessels"],"prefix":"10.1002","volume":"90","author":[{"given":"Francesco","family":"Giannini","sequence":"first","affiliation":[{"name":"Interventional Cardiology Unit San Raffaele Scientific Institute Milan Italy"},{"name":"Interventional Cardiology Unit EMO\u2010GVM Centro Cuore Columbus Milan 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