{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T09:35:05Z","timestamp":1777023305836,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,3,15]],"date-time":"2017-03-15T00:00:00Z","timestamp":1489536000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The impact of hospital volume on long\u2010term outcome after carotid artery stenting (CAS) remains unknown.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We designed a nationwide cohort study to elucidate the impact of hospital volume on the incidence of stroke after CAS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The Taiwan National Health Insurance Research database was used to identify all patients admitted for CAS from 2008 to 2012. We defined high\u2010volume hospitals as those performing more than 20 CAS per year. The primary outcome was new ischemic stroke after discharging from the index CAS. Propensity score\u2010matching was performed to create two matched groups for comparison.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 3,248 patients underwent 3,576 CAS procedures were enrolled. There were 56 hospitals performing CAS during the study period. Among these 3,248 patients, 2,226 (68.5%) were performed in high\u2010volume hospitals. A propensity score\u2010matching created two groups with 1,000 patients in each group. During a median of 2.06 years follow\u2010up, 35 (3.5%) and 52 (5.2%) patients in high\u2010volume hospitals and low\u2010volume hospitals developed new ischemic stroke 30 days after discharging from the index CAS, respectively (for low\u2010volume hospitals, HR 1.50, 95%CI 1.06\u20132.12, <jats:italic>P<\/jats:italic>\u2009=\u20090.023). The use of embolic protection device did not result in different periprocedural or postdischarge strokes. The periprocedural (within 30 days after CAS) ischemic stroke or all\u2010cause mortality rates during follow\u2010up period were similar between two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>CAS performed in high\u2010volume hospitals was associated with less new ischemic stroke after discharging from the index CAS, compared to those in low\u2010volume hospitals. \u00a9 2017 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.26989","type":"journal-article","created":{"date-parts":[[2017,3,15]],"date-time":"2017-03-15T12:47:58Z","timestamp":1489582078000},"page":"1242-1249","source":"Crossref","is-referenced-by-count":4,"title":["Impact of hospital volume on long\u2010term neurological outcome in patients undergoing carotid artery stenting"],"prefix":"10.1002","volume":"89","author":[{"given":"Chi\u2010Sheng","family":"Hung","sequence":"first","affiliation":[{"name":"Department of Internal Medicine National Taiwan University Hospital Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chih\u2010Fan","family":"Yeh","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine National Taiwan University Hospital Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mao\u2010Shin","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine National Taiwan University Hospital Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying\u2010Hsien","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine National Taiwan University Hospital Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ching\u2010Chang","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine National Taiwan University Hospital Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hung\u2010Yuan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine National Taiwan University Hospital Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsien\u2010Li","family":"Kao","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine National Taiwan University Hospital Taipei 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