{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:35:11Z","timestamp":1761863711661,"version":"3.37.3"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,6,2]],"date-time":"2017-06-02T00:00:00Z","timestamp":1496361600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study aimed to evaluate the amount and pattern of cardiac biomarker release after elective percutaneous coronary intervention (PCI) in patients without evidence of a new myocardial infarction (MI) after the procedure as assessed by cardiac magnetic resonance (CMR) with late gadolinium enhancement (LGE).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>The release of myocardial necrosis biomarkers after PCI frequently occurs. However, the correlation between biomarker release and the diagnosis of procedure\u2010related MI type 4a has been controversial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with normal baseline cardiac biomarkers who were referred for elective PCI were prospectively included. CMR with LGE was performed in all of the patients before and after the intervention. Measurements of troponin I (TnI) and creatine kinase MB fraction (CK\u2010MB) were systematically performed before and after the procedure. Patients with a new LGE on the post\u2010procedure CMR were excluded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 56 patients with no evidence of a procedure\u2010related MI as assessed by CMR after the PCI, 48 (85.1%) exhibited an elevation of TnI above the 99th percentile. In 32 patients (57.1%), the peak was greater than five times this limit. Additionally, 17 patients (30.4%) had a CK\u2010MB peak above the 99th percentile limit, but this peak was greater than five times the 99th percentile in only two patients (3.6%). The median peak release of TnI was 0.290 (0.061\u20131.09) ng\/mL, which was 7.25\u2010fold higher than the 99th percentile.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In contrast to CK\u2010MB, an abnormal release of TnI often occurs after an elective PCI procedure, despite the absence of a new LGE on CMR.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27125","type":"journal-article","created":{"date-parts":[[2017,6,2]],"date-time":"2017-06-02T08:52:37Z","timestamp":1496393557000},"page":"87-93","source":"Crossref","is-referenced-by-count":2,"title":["Biomarker release after percutaneous coronary intervention in patients without established myocardial infarction as assessed by cardiac magnetic resonance with late gadolinium enhancement"],"prefix":"10.1002","volume":"90","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3927-778X","authenticated-orcid":false,"given":"Rodrigo Morel","family":"Vieira de Melo","sequence":"first","affiliation":[{"name":"Department of Atherosclerosis Heart Institute (InCor) of the University of S\u00e3o Paulo S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Whady","family":"Hueb","sequence":"additional","affiliation":[{"name":"Department of Atherosclerosis Heart Institute (InCor) of the University of S\u00e3o Paulo S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cesar Higa","family":"Nomura","sequence":"additional","affiliation":[{"name":"Department of Atherosclerosis Heart Institute (InCor) of the University of S\u00e3o Paulo S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Expedito Eust\u00e1quio","family":"Ribeiro da Silva","sequence":"additional","affiliation":[{"name":"Department of Atherosclerosis Heart Institute (InCor) of the University of S\u00e3o Paulo S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre Volney","family":"Villa","sequence":"additional","affiliation":[{"name":"Department of Atherosclerosis Heart Institute (InCor) of the University of S\u00e3o Paulo S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando Teiichi Costa","family":"Oikawa","sequence":"additional","affiliation":[{"name":"Department of Atherosclerosis Heart Institute (InCor) of the University of S\u00e3o Paulo S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leandro Menezes Alves","family":"da Costa","sequence":"additional","affiliation":[{"name":"Department of Atherosclerosis Heart Institute (InCor) of the University of S\u00e3o Paulo S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo Cury","family":"Rezende","sequence":"additional","affiliation":[{"name":"Department of Atherosclerosis Heart Institute (InCor) of the University of S\u00e3o Paulo S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cibele Larrosa","family":"Garzillo","sequence":"additional","affiliation":[{"name":"Department of Atherosclerosis Heart Institute (InCor) of the University of S\u00e3o Paulo S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo Gomes","family":"Lima","sequence":"additional","affiliation":[{"name":"Department of Atherosclerosis Heart Institute (InCor) of the University of S\u00e3o Paulo S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Antonio","family":"Franchini Ramires","sequence":"additional","affiliation":[{"name":"Department of Atherosclerosis Heart Institute (InCor) of the University of S\u00e3o Paulo S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Kalil Filho","sequence":"additional","affiliation":[{"name":"Department of Atherosclerosis Heart Institute (InCor) of the University of S\u00e3o Paulo S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,6,2]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi455"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.627505"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.110.959080"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.07.058"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2009.186189"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e31826e1058"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.2001.2976"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00298-3"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.708529"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.752428"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.03.063"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.108.765610"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.110.957712"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2014.159"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12389-6"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.97.8.765"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.08.047"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.03.035"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1161\/hc2301.092121"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2261-12-65"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/10976640500295516"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-0736(10)80041-X"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(89)90420-7"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi173"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2011.2275"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.723262"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)03567-4"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/1532-429X-14-15"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.21272"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2012.11.013"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.111.963421"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1080\/10976640701545008"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq456"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.06.243"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2007.097162"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2004.05.076"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.11.066"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2009.173302"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.27125","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.27125","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.27125","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.27125","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T16:44:58Z","timestamp":1693241098000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.27125"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,2]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["10.1002\/ccd.27125"],"URL":"https:\/\/doi.org\/10.1002\/ccd.27125","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"type":"print","value":"1522-1946"},{"type":"electronic","value":"1522-726X"}],"subject":[],"published":{"date-parts":[[2017,6,2]]}}}