{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:36:05Z","timestamp":1786977365880,"version":"build-2736575974"},"reference-count":43,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,7,14]],"date-time":"2017-07-14T00:00:00Z","timestamp":1499990400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To examine the relationship between occupational exposure to ionizing radiation and the prevalence of lens changes in interventional cardiologists (ICs) and catheterization laboratory (\u201ccath\u2010lab\u201d) staff.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Exposure to ionizing radiation is associated with the development of lens opacities. ICs and cath\u2010lab staff can receive high doses of ionizing radiation without protection, and may thus be at risk for lens opacity formation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a cross\u2010sectional study at an interventional cardiology conference. Study participants completed a questionnaire pertaining to occupational exposure to radiation and potential confounders for the development of cataracts, followed by slit\u2010lamp examination and grading of lens findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 117 attendees participated in the study, including 99 (85%; 49\u2009\u00b1\u200911 years\u2010old; 82% male) with occupational exposure to ionizing radiation and 18 (15%; 39\u2009\u00b1\u200912 years\u2010old; 61% male) unexposed controls. The prevalence of overall cortical and posterior subcapsular lens changes (including subclinical findings) was higher in exposed participants compared with controls (47 vs. 17%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.015). Occupational exposure and age over 60 were independent predictors of lens changes (odds ratio [95% CI]: 6.07 [1.38\u201343.45] and 7.72 [1.60\u201343.34], respectively). The prevalence of frank opacities was low and similar between the two groups (14 vs. 6%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.461). Most lens findings consisted of subclinical changes in the periphery of the lens without impact on visual acuity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Compared with unexposed controls, ICs and cath\u2010lab staff had a higher prevalence of lens changes that may be attributable to ionizing radiation exposure. While most of these changes were subclinical, they are important due to the potential to progress to clinical symptoms, highlighting the importance of minimizing staff radiation exposure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.27173","type":"journal-article","created":{"date-parts":[[2017,7,14]],"date-time":"2017-07-14T03:33:09Z","timestamp":1500003189000},"page":"647-654","source":"Crossref","is-referenced-by-count":46,"title":["Radiation\u2010associated lens changes in the cardiac catheterization laboratory: Results from the IC\u2010CATARACT (CATaracts Attributed to RAdiation in the CaTh lab) study"],"prefix":"10.1002","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5468-3941","authenticated-orcid":false,"given":"Aris","family":"Karatasakis","sequence":"first","affiliation":[{"name":"Department of Cardiology VA North Texas Healthcare System and University of Texas Southwestern Medical Center Dallas Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harilaos S.","family":"Brilakis","sequence":"additional","affiliation":[{"name":"Cosmos Eye Center Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara A.","family":"Danek","sequence":"additional","affiliation":[{"name":"Department of Cardiology VA North Texas Healthcare System and University of Texas Southwestern Medical Center Dallas Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7389-7734","authenticated-orcid":false,"given":"Judit","family":"Karacsonyi","sequence":"additional","affiliation":[{"name":"Department of Cardiology VA North Texas Healthcare System and University of Texas Southwestern Medical Center Dallas Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1221-9977","authenticated-orcid":false,"given":"Jose Roberto","family":"Martinez\u2010Parachini","sequence":"additional","affiliation":[{"name":"Department of Cardiology VA North Texas Healthcare System and University of Texas Southwestern Medical Center Dallas Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phuong\u2010Khanh J.","family":"Nguyen\u2010Trong","sequence":"additional","affiliation":[{"name":"Department of Cardiology VA North Texas Healthcare System and University of Texas Southwestern Medical Center Dallas Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aya J.","family":"Alame","sequence":"additional","affiliation":[{"name":"Department of Cardiology VA North Texas Healthcare System and University of Texas Southwestern Medical Center Dallas Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele K.","family":"Roesle","sequence":"additional","affiliation":[{"name":"Department of Cardiology VA North Texas Healthcare System and University of Texas Southwestern Medical Center Dallas Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bavana V.","family":"Rangan","sequence":"additional","affiliation":[{"name":"Department of Cardiology VA North Texas Healthcare System and University of Texas Southwestern Medical Center Dallas Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5633-6983","authenticated-orcid":false,"given":"Kenneth","family":"Rosenfield","sequence":"additional","affiliation":[{"name":"Division of Cardiology Massachusetts General Hospital Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxana","family":"Mehran","sequence":"additional","affiliation":[{"name":"Division of Cardiology Icahn School of Medicine at Mount Sinai New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ehtisham","family":"Mahmud","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine University of California San Diego La Jolla California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles E.","family":"Chambers","sequence":"additional","affiliation":[{"name":"Heart and Vascular Institute Penn State Milton S. Hershey Medical Center Hershey Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subhash","family":"Banerjee","sequence":"additional","affiliation":[{"name":"Department of Cardiology VA North Texas Healthcare System and University of Texas Southwestern Medical Center Dallas Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9416-9701","authenticated-orcid":false,"given":"Emmanouil S.","family":"Brilakis","sequence":"additional","affiliation":[{"name":"Department of Cardiology VA North Texas Healthcare System and University of Texas Southwestern Medical Center Dallas Texas"},{"name":"Minneapolis Heart Institute at Abbott Northwestern Hospital Minneapolis Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,7,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.81.4.257"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.2307\/3580093"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.81.4.261"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.83.4.588"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.123.8.1102"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1667\/0033-7587(2001)156[0460:SRACIA]2.0.CO;2"},{"key":"e_1_2_6_8_1","first-page":"A56","article-title":"Cataract formation mechanisms and risk in aviation and space crews","volume":"78","author":"Jones JA","year":"2007","journal-title":"Aviat Space Environ Med"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.HP.0000175442.03596.63"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/09553000410001680332"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1667\/RR3183"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1667\/RR0298.1"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2005.06.015"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/76128583"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.HP.0000290614.76386.35"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0720-048X(03)00007-X"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2482071800"},{"key":"e_1_2_6_18_1","article-title":"Cataract in Interventional Radiology \u2013 an Occupational Hazard? (Abstract)","volume":"45","author":"Junk AK","year":"2004","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.22670"},{"key":"e_1_2_6_20_1","article-title":"Radiation eye injuries in medical staff working with fluoroscopy guided procedures in Bulgaria","author":"Vassileva J.","year":"2010","journal-title":"Eur Soc Radiol (Abstract)"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1667\/RR2207.1"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.3152"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1159\/000342458"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.04.124"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2012.10.016"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.5812\/cardiovascmed.25148"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.115.003273"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.71.849.10195011"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/26829723"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/rpd\/ncq039"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.20451"},{"key":"e_1_2_6_32_1","first-page":"35","article-title":"A clinical and experimental study of the effect of single and divided doses of radiation on cataract production","volume":"60","author":"Merriam GR","year":"1962","journal-title":"Trans Am Ophthalmol Soc"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1076\/opep.9.2.83.1523"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1667\/RR1688.1"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.icrp.2012.02.001"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2014.07.049"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1097\/HP.0000000000000412"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2011.349"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.22867"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2010.01.007"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.asr.2004.12.032"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1667\/rr1122.1"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.24520"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2010.07.019"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.27173","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.27173","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T13:09:39Z","timestamp":1695647379000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.27173"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,14]]},"references-count":43,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["10.1002\/ccd.27173"],"URL":"https:\/\/doi.org\/10.1002\/ccd.27173","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7,14]]}}}