{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T10:34:09Z","timestamp":1787654049070,"version":"build-2736575974"},"reference-count":21,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,11,24]],"date-time":"2017-11-24T00:00:00Z","timestamp":1511481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"JenaValve Technologies GmbH"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We present 1\u2010year outcomes of the post\u2010market registry of a next\u2010generation transcatheter heart valve used for aortic regurgitation (AR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Transcatheter aortic valve replacement (TAVR) is routine in high\u2010risk patients with aortic stenosis but is not recommended for AR. The JenaValve\u2122 (JenaValve Technology GmbH, Munich, Germany) overcomes technical challenges in AR patients through a leaflet clipping mechanism.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The JenaValve EvalUation of Long Term Performance and Safety In PaTients with SEvere Aortic Stenosis oR Aortic Insufficiency (JUPITER) Registry is a European study to evaluate safety and effectiveness of this THV. From 2012\u20102015, 30 patients with AR were enrolled.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean age was 74.4\u2009\u00b1\u20099.3 years. Procedural success was 96.7% (29\/30). One patient was converted to open surgery. No annular rupture or coronary ostia obstruction occurred. Mortality at 30 days was 10.0% (3\/30). Combined safety endpoint was met in 13.3% (4\/30). Paravalvular regurgitation was not present\/trivial in 84.6% (22\/26) and mild in 15.4% (4\/26). Rate of permanent pacemaker implantation was 3.8% (1\/26). One\u2010year Kaplan\u2010Meier survival was 79.9%, one\u2010year combined efficacy was 73.1% (19\/30). No further strokes were observed during 1 year of follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The JenaValve overcomes technical challenges of TAVR in AR through a clipping mechanism. We report satisfactory outcomes of a multicenter registry using the JenaValve for predominant AR, as rate of THV embolization, residual AR and permanent pacemaker implantation was low. One\u2010year results using the JenaValve for AR encourage its use for this indication.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27370","type":"journal-article","created":{"date-parts":[[2017,11,24]],"date-time":"2017-11-24T12:46:03Z","timestamp":1511527563000},"page":"1345-1351","source":"Crossref","is-referenced-by-count":48,"title":["The JUPITER registry: One\u2010year outcomes of transapical aortic valve implantation using a second generation transcatheter heart valve for aortic regurgitation"],"prefix":"10.1002","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7293-5516","authenticated-orcid":false,"given":"Miriam","family":"Silaschi","sequence":"first","affiliation":[{"name":"Department of Cardiac Surgery University Hospital Halle (Saale) Halle Saale Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lenard","family":"Conradi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery University Heart Center Hamburg Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olaf","family":"Wendler","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery King's College Hospital London London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Friederike","family":"Schlingloff","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery Asklepios Klinik St. Georg Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Utz","family":"Kappert","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery University Heart Center Dresden Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ardawan J","family":"Rastan","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery Center of Cardiovascular Diseases Rotenburg a. d. 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