{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T08:21:19Z","timestamp":1765268479190,"version":"3.37.3"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,11,11]],"date-time":"2017-11-11T00:00:00Z","timestamp":1510358400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this investigation was to identify patient's characteristics and periprocedural variables related to periprocedural transfusion in transfemoral Transcatheter Aortic Valve Implantation (tf\u2010TAVI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Transfusion of allogenic red\u2010blood cells (RBC) in tf\u2010TAVI and the number of transfused units has been linked to an increased 30\u2010day mortality. In line with the trend of minimization and cost\u2010effectiveness, transfusion should be avoided, wherever possible.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between 2007 and 2015, 1,734 procedures were analyzed from our prospective registry for RBC\u2010transfusion. Multiple logistic regression analysis was used to identify the dependent variables.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Transfusion was considered necessary in 14% (<jats:italic>n<\/jats:italic>\u2009=\u2009243) of the patients. Female gender (OR [95% CI]) (1.680 [1.014\u20102.783]) and preprocedural moderate (7.594 [4.404\u201013.095]) and severe anemia (8.202 [0.900\u201074.752]) according to WHO were the most important preprocedural variables. Periprocedural, pericardial effusion (12.109 [3.753\u201039.063]), emergency extracorporeal circulation (54.5288 [6.178\u2010481.259]) and major vascular injury (2.647 [1.412\u20104.962]) were related to transfusion. The same applies to moderate (4.255 [1.859\u20109.740]) and severe anemia (31.567 [8.560\u2010116.416]) as well as periprocedural experience (0.072 [0.035\u20100.149] \u2013 0.141[0.079\u20100.251], <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001)<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Procedural experience, serious adverse events, low pre\u2010 and periprocedural Hb levels and female gender were the main variables relating to transfusion. Even in experienced high\u2010volume centers, transfusion is still necessary in a considerable number of patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27382","type":"journal-article","created":{"date-parts":[[2017,11,11]],"date-time":"2017-11-11T13:08:53Z","timestamp":1510405733000},"page":"141-148","source":"Crossref","is-referenced-by-count":1,"title":["Periprocedural transfusion in patients undergoing transfemoral transcatheter aortic valve implantation"],"prefix":"10.1002","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3549-3007","authenticated-orcid":false,"given":"N Patrick","family":"Mayr","sequence":"first","affiliation":[{"name":"Institut f\u00fcr An\u00e4sthesiologie, Deutsches Herzzentrum M\u00fcnchen des Freistaates Bayern, Technische Universit\u00e4t M\u00fcnchen, Lazarettstr. 36 Munich D\u201080636 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