{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:56:47Z","timestamp":1787011007146,"version":"build-2736575974"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,11,6]],"date-time":"2017-11-06T00:00:00Z","timestamp":1509926400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We sought to assess angiographic, echocardiographic and hemodynamic grading of paravalvular leakage (PVL) after transcatheter aortic valve implantation (TAVI) with respect to prediction of 1\u2010year mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Meaningful criteria for the severity of PVL are needed to allow intraprocedural guidance and patient management after TAVI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We pooled the prospective TAVI databases of 2 German centers. During TAVI, PVL was assessed angiographically and by the aortic regurgitation index (ARI). ARI was calculated as ratio of the gradient between diastolic blood pressure and left ventricular end\u2010diastolic pressure to systolic blood pressure times hundred. In addition, we performed transthoracic echocardiography before discharge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 723 patients undergoing TAVI with self\u2010expandable (20.9%) or balloon\u2010expandable (79.1%) valves were included. Grades of PVL as assessed during the procedure by angiography or ARI (below the previously defined cut\u2010off of 25) did not show a significant association with 1\u2010year mortality (<jats:italic>P<\/jats:italic>\u2009=\u20090.312 and 0.776, respectively). One\u2010year mortality was 15.7% (39\/249) in patienths with an ARI\u2009&lt;\u200925 and 16.5% (71\/430) in patients with an ARI\u2009\u2265\u200925. Echocardiographic classes of PVL at discharge showed a significant (<jats:italic>P<\/jats:italic>\u2009=\u20090.029) association with 1\u2010year mortality, which was 11.5% (37\/322) in patients with no\/trace PVL, 18.0% (62\/345) in patients with mild PVL and 23.1% (6\/26) in patients with more than mild PVL. These findings prevailed after multivariable adjustment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>ARI did not help identify PVLs that are relevant to 1\u2010year survival. Angiographic assessment during the procedure was less predictive than echocardiographic assessment before discharge.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27384","type":"journal-article","created":{"date-parts":[[2017,11,6]],"date-time":"2017-11-06T06:12:45Z","timestamp":1509948765000},"source":"Crossref","is-referenced-by-count":8,"title":["Hemodynamic classification of paravalvular leakage after transcatheter aortic valve implantation compared with angiographic or echocardiographic classification for prediction of 1\u2010year mortality"],"prefix":"10.1002","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0785-8846","authenticated-orcid":false,"given":"Simon","family":"Schoechlin","sequence":"first","affiliation":[{"name":"Department of Cardiology &amp; Angiology II University Heart Center Freiburg\u2010Bad Krozingen  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Brennemann","sequence":"additional","affiliation":[{"name":"Department of Cardiology &amp; Angiology II University Heart Center Freiburg\u2010Bad Krozingen  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdelhakim","family":"Allali","sequence":"additional","affiliation":[{"name":"Department of Cardiology Heart Center Bad Segeberg, Segeberger Kliniken  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3379-5797","authenticated-orcid":false,"given":"Philip","family":"Ruile","sequence":"additional","affiliation":[{"name":"Department of Cardiology &amp; Angiology II University Heart Center Freiburg\u2010Bad Krozingen  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaus","family":"Jander","sequence":"additional","affiliation":[{"name":"Department of Cardiology &amp; Angiology II University Heart Center Freiburg\u2010Bad Krozingen  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Allgeier","sequence":"additional","affiliation":[{"name":"Department of Cardiology &amp; Angiology II University Heart Center Freiburg\u2010Bad Krozingen  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Gick","sequence":"additional","affiliation":[{"name":"Department of Cardiology &amp; Angiology II University Heart Center Freiburg\u2010Bad Krozingen  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gert","family":"Richardt","sequence":"additional","affiliation":[{"name":"Department of Cardiology Heart Center Bad Segeberg, Segeberger Kliniken  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franz\u2010Josef","family":"Neumann","sequence":"additional","affiliation":[{"name":"Department of Cardiology &amp; Angiology II University Heart Center Freiburg\u2010Bad Krozingen  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Abdel\u2010Wahab","sequence":"additional","affiliation":[{"name":"Department of Cardiology Heart Center Bad Segeberg, Segeberger Kliniken  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,11,6]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.009834"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)60290-2"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2010.217158"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu162"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2012.04.011"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.07.006"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2009.07.013"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.02.088"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV7I8A12"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.11.048"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2015.12.271"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.09.026"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.3316"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2014.07.019"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn183"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.13120696"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2010.03.039"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.632927"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs255"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq406"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.01.047"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jew083"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)00644-X"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2006.06.011"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2015.01.008"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00807.2012"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.25848"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2016.02.012"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.27384","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.27384","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T22:19:43Z","timestamp":1695507583000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.27384"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,6]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,5]]}},"alternative-id":["10.1002\/ccd.27384"],"URL":"https:\/\/doi.org\/10.1002\/ccd.27384","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,6]]}}}