{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:51:41Z","timestamp":1761562301558,"version":"3.37.3"},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,11,11]],"date-time":"2017-11-11T00:00:00Z","timestamp":1510358400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although the incidence of periprocedural complications has decreased in transcatheter aortic valve implantation (TAVI), life\u2010threatening complications occur and emergency veno\u2010arterial extracorporeal membrane oxygenation (vaECMO) can provide immediate circulatory stabilization. We report our two\u2010center experience of vaECMO during life\u2010threatening complications in TAVI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From January 2010 to December 2015, 1,810 consecutive patients underwent TAVI at two centers. Clinical characteristics, type of complication, outcome and temporal trends in the requirement of emergency vaECMO were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Life\u2010threatening complications requiring vaECMO occurred in 1.8% of cases (33 patients; 22 transfemoral, 11 transapical). Indications for vaECMO were ventricular rupture (30%, 10\/33), low output (15%, 5\/33), bleeding (12%, 4\/33), coronary artery impairment (9%, 3\/33), ventricular arrhythmias (6%, 2\/33), severe aortic regurgitation (6%, 2\/33), aortic annular rupture (6%, 2\/33), and aortic dissection (3%, 1\/33). In 4 cases, no definite cause for hemodynamic instability was identified. Conversion to open heart surgery was necessary in 42% of patients (14\/33). Percutaneous coronary intervention was performed in all cases with coronary artery impairment (9%, 3\/33). Patients with severe aortic regurgitation (6%, 2\/33) underwent emergency valve\u2010in\u2010valve implantation. Other patients received, in addition to vaECMO support conservative treatment (42%, 14\/33). In\u2010hospital mortality and 30\u2010day mortality were 46% (15\/33). Of patients discharged, 67% (12\/18) had no neurological impairment, whereas mild and severe neurological impairment was found in 11% (2\/18) and 22% (4\/18), respectively. From 2010 to 2015, with increasing procedures (from n\u2009=\u200943 to n\u2009=\u2009553) requirement of vaECMO decreased from 9.3% to 0.9% (<jats:italic>P<\/jats:italic> for the trend &lt;0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Over a 6\u2010year period, need for emergency vaECMO during TAVI significantly decreased over time. Despite high in\u2010hospital mortality, vaECMO represents a feasible strategy for hemodynamic support in case of life\u2010threatening complications.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27385","type":"journal-article","created":{"date-parts":[[2017,11,11]],"date-time":"2017-11-11T13:08:48Z","timestamp":1510405728000},"page":"149-156","source":"Crossref","is-referenced-by-count":20,"title":["Emergency extracorporeal membrane oxygenation in transcatheter aortic valve implantation: A two\u2010center experience of incidence, outcome and temporal trends from 2010 to 2015"],"prefix":"10.1002","volume":"92","author":[{"given":"Teresa","family":"Trenkwalder","sequence":"first","affiliation":[{"name":"Klinik f\u00fcr Herz\u2010 und Kreislauferkrankungen, Deutsches Herzzentrum M\u00fcnchen Technical University Munich Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5143-8203","authenticated-orcid":false,"given":"Costanza","family":"Pellegrini","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Herz\u2010 und Kreislauferkrankungen, Deutsches Herzzentrum M\u00fcnchen Technical University Munich Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Holzamer","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Herz\u2010, Thorax\u2010 und herznahe Gef\u00e4\u00dfchirurgie University of Regensburg Medical Center Regensburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alois","family":"Philipp","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Herz\u2010, Thorax\u2010 und herznahe Gef\u00e4\u00dfchirurgie University of Regensburg Medical Center Regensburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tobias","family":"Rheude","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Herz\u2010 und Kreislauferkrankungen, Deutsches Herzzentrum M\u00fcnchen Technical University Munich Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Michel","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Herz\u2010 und Kreislauferkrankungen, Deutsches Herzzentrum M\u00fcnchen Technical University Munich Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wibke","family":"Reinhard","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Herz\u2010 und Kreislauferkrankungen, Deutsches Herzzentrum M\u00fcnchen Technical University Munich Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Joner","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Herz\u2010 und Kreislauferkrankungen, Deutsches Herzzentrum M\u00fcnchen Technical University Munich Munich Germany"},{"name":"Deutsches Zentrum f\u00fcr Herz\u2010 und Kreislauf\u2010Forschung (DZHK) e.V. 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