{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T02:10:10Z","timestamp":1740103810068,"version":"3.37.3"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,10,25]],"date-time":"2017-10-25T00:00:00Z","timestamp":1508889600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2018,2,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Data on the clinical performance of bioresorbable scaffolds in patients with diabetes mellitus (DM) are still limited. The present study reported 1\u2010year clinical outcomes associated with the use of everolimus\u2010eluting bioresorbable vascular scaffolds (Absorb BVS; Abbott Vascular, Santa Clara, CA) in DM patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>This was a subanalysis from the GHOST\u2010EU (Gauging coronary Healing with biOresorbable Scaffolding plaTforms in Europe) multicenter retrospective registry including patients treated with Absorb BVS between November 2011 and September 2014. In this study, a comparative analysis stratified according to DM was performed. The primary endpoint was target lesion failure (TLF), defined as the combination of cardiac death, target\u2010vessel myocardial infarction (MI) and clinically\u2010driven target\u2010lesion revascularization (TLR). A total of 1,477 patients were treated with 2,224 Absorb BVS; 381 (25.8%) and 1,096 (74.2%) patients were with and without DM, respectively. The 1\u2010year rate of TLF was higher among patients with DM (7.8%) than those without DM (4.3%); the increase in TLF was driven by TLR (6.5% vs. 3.3%, <jats:italic>P<\/jats:italic>\u2009=\u20090.009); no significant differences in cardiac death (1.1% vs. 0.9%, <jats:italic>P<\/jats:italic>\u2009=\u20090.68) and target\u2010vessel MI (3.1% vs. 2.2%, <jats:italic>P<\/jats:italic>\u2009=\u20090.38) were observed, respectively. Definite\/probable scaffold thrombosis rate tended to be higher among patients with DM than those without DM (3.0% vs. 1.7%, <jats:italic>P<\/jats:italic>\u2009=\u20090.14, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Absorb BVS use in patients with DM was associated with increased 1\u2010year TLF and scaffold thrombosis compared with non\u2010diabetes patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27388","type":"journal-article","created":{"date-parts":[[2017,10,25]],"date-time":"2017-10-25T11:43:10Z","timestamp":1508931790000},"page":"444-453","source":"Crossref","is-referenced-by-count":6,"title":["Clinical outcomes of patients with diabetes mellitus treated with Absorb bioresorbable vascular scaffolds: a subanalysis of the <scp>E<\/scp>uropean <scp>M<\/scp>ulticentre <scp>GHOST<\/scp>\u2010<scp>EU<\/scp><scp>R<\/scp>egistry"],"prefix":"10.1002","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8434-7367","authenticated-orcid":false,"given":"Piera","family":"Capranzano","sequence":"first","affiliation":[{"name":"Cardiovascular department Ferrarotto Hospital, University of Catania Catania Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davide","family":"Capodanno","sequence":"additional","affiliation":[{"name":"Cardiovascular department Ferrarotto Hospital, University of Catania Catania Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5845-1435","authenticated-orcid":false,"given":"Salvatore","family":"Brugaletta","sequence":"additional","affiliation":[{"name":"Department of Cardiology Clinic Cardiovascular Institute, Hospital Clinic, Biomedical Investigation Institute, IDIBAPS, University of Barcelona  Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azeem","family":"Latib","sequence":"additional","affiliation":[{"name":"EMO\u2010GVM Centro Cuore and San Raffaele Hospitals Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8750-5567","authenticated-orcid":false,"given":"Julinda","family":"Mehilli","sequence":"additional","affiliation":[{"name":"Department of Cardiology Klinikum Gro\u00dfhadern, Ludwig\u2010Maximilian Universit\u00e4t Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Holger","family":"Nef","sequence":"additional","affiliation":[{"name":"Department of Cardiology University of Giessen Giessen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tommaso","family":"Gori","sequence":"additional","affiliation":[{"name":"Zentrum f\u00fcr Kardiologie I, Universit\u00e4tsmedizin Mainz, University Medical Center, and German Center for Cardiovascular Research (DZHK, Standort Rhein\u2010Main) Mainz Germany"},{"name":"Center for Thrombosis and Hemostasis, University Medical Center Mainz Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maciej","family":"Lesiak","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Medical Sciences Poznan Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore","family":"Geraci","sequence":"additional","affiliation":[{"name":"San Giovanni di Dio Hospital Agrigento Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2062-9351","authenticated-orcid":false,"given":"Stelios","family":"Pyxaras","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Kardiologie und Angiologie, Elisabeth\u2010Krankenhaus Essen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessio","family":"Mattesini","sequence":"additional","affiliation":[{"name":"Careggi Hospital, University of Florence Florence Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"M\u00fcnzel","sequence":"additional","affiliation":[{"name":"Zentrum f\u00fcr Kardiologie I, Universit\u00e4tsmedizin Mainz, University Medical Center, and German Center for Cardiovascular Research (DZHK, Standort Rhein\u2010Main) Mainz Germany"},{"name":"Center for Thrombosis and Hemostasis, University Medical Center Mainz Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6409-6441","authenticated-orcid":false,"given":"Aleksander","family":"Araszkiewicz","sequence":"additional","affiliation":[{"name":"National Institute of Health Research Cardiovascular BRU, Royal Brompton Hospital &amp; 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