{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T13:46:15Z","timestamp":1771854375264,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,11,6]],"date-time":"2017-11-06T00:00:00Z","timestamp":1509926400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Compare final morphology of self\u2010expanding and balloon\u2010expandable prosthesis and association with paravalvular regurgitation (PVR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>PVR after transcatheter aortic valve replacement (TAVR) remains a frequent complication. A better understanding of the prosthesis geometry may be important to improve selection of the best device for each case and possibly reduce the rates of PVR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective study including patients consecutively submitted to transcatheter aortic valve replacement: August\/2007\u2010October\/2016. Three months after the procedure a multidetector computed tomography (MDCT) was performed to assess prosthesis geometry: dimensions, eccentricity, and expansion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 147 individuals were included (mean age of 78.8\u2009\u00b1\u20096.7 and 50.3% males), 57% treated with a self\u2010expanding prosthesis. On the postprocedure MDCT, the self\u2010expanding group had higher eccentricity index (15.0 vs. 7.1%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) and lower expansion (68.3 vs. 82.8%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). In that group, the volume of calcium of landing zone had a significant correlation with eccentricity index and under\u2010expansion. Patients with \u2265mild PVR presented higher eccentricity (12.6 vs. 7.9%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) and lower expansion (68 vs. 75%, <jats:italic>p<\/jats:italic>\u2009=\u2009.012). Eccentricity index and landing zone calcium volume were independent predictors of PVR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Self\u2010expanding prosthesis have greater eccentricity and under\u2010expansion. Calcium burden exerts more influence in the final morphology of that type of valve. Calcification and eccentricity are associated with the development of PVR. These factors should be considered in the selection of the most appropriate type of prosthesis for each scenario.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27401","type":"journal-article","created":{"date-parts":[[2017,11,6]],"date-time":"2017-11-06T06:12:50Z","timestamp":1509948770000},"page":"533-541","source":"Crossref","is-referenced-by-count":16,"title":["Comparison of self\u2010expanding and balloon\u2010expandable transcatheter aortic valves morphology and association with paravalvular regurgitation: Evaluation using multidetector computed tomography"],"prefix":"10.1002","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9434-7061","authenticated-orcid":false,"given":"Jo\u00e3o G.","family":"Almeida","sequence":"first","affiliation":[{"name":"Department of Cardiology Gaia\/Espinho Hospital Center, Rua Concei\u00e7\u00e3o Fernandes Vila Nova de Gaia 4434\u2010502 Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara M.","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Department of Cardiology Divino Espirito Santo Hospital Ponta Delgada Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo","family":"Fonseca","sequence":"additional","affiliation":[{"name":"Department of Cardiology Gaia\/Espinho Hospital Center, Rua Concei\u00e7\u00e3o Fernandes Vila Nova de Gaia 4434\u2010502 Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiago","family":"Dias","sequence":"additional","affiliation":[{"name":"Department of Cardiology Gaia\/Espinho Hospital Center, Rua Concei\u00e7\u00e3o Fernandes Vila Nova de Gaia 4434\u2010502 Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4825-0979","authenticated-orcid":false,"given":"Cl\u00e1udio","family":"Guerreiro","sequence":"additional","affiliation":[{"name":"Department of Cardiology Gaia\/Espinho Hospital Center, Rua Concei\u00e7\u00e3o Fernandes Vila Nova de Gaia 4434\u2010502 Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Barbosa","sequence":"additional","affiliation":[{"name":"Department of Cardiology Gaia\/Espinho Hospital Center, Rua Concei\u00e7\u00e3o Fernandes Vila Nova de Gaia 4434\u2010502 Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Teixeira","sequence":"additional","affiliation":[{"name":"Department of Cardiology Gaia\/Espinho Hospital Center, Rua Concei\u00e7\u00e3o Fernandes Vila Nova de Gaia 4434\u2010502 Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00f3nica","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Department of Cardiology Gaia\/Espinho Hospital Center, Rua Concei\u00e7\u00e3o Fernandes Vila Nova de Gaia 4434\u2010502 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