{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T15:02:06Z","timestamp":1788188526963,"version":"build-2803163510"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,11,15]],"date-time":"2017-11-15T00:00:00Z","timestamp":1510704000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Correlations between the ACC\/AHA coronary lesion classification and clinical outcomes in the contemporary percutaneous coronary intervention (PCI) era are not well established.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analyzed clinical characteristics and outcomes according to ACC\/AHA lesion classification (A, B1, B2, C) in 13,701 consecutive patients from the Melbourne Interventional Group (MIG) registry. Patients presenting with STEMI, cardiogenic shock and out\u2010of\u2010hospital cardiac arrest were excluded. The primary endpoints were 30\u2010day and 12\u2010month mortality. Secondary endpoints were procedural success as well as 30\u2010day and 12\u2010month major adverse cardiac events.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 13,701 patients treated, 1,246 (9.1%) had type A lesions, 5,519 (40.3%) had type B1 lesions, 4,449 (32.5%) had Type B2 lesions and 2,487 (18.2%) had Type C lesions. Patients with type C lesions were more likely to be older and have impaired renal function, diabetes, previous myocardial infarction, peripheral vascular disease and prior bypass graft surgery (all <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). They were also more likely to require rotational atherectomy, drug\u2010eluting stents and longer stent lengths (all <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). Increasing lesion complexity was associated with lower procedural success (99.6% vs. 99.1% vs. 96.6% vs. 82.7%, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and worse 30\u2010day (0.2% vs. 0.3% vs. 0.7% vs. 0.6%, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and 12\u2010month mortality (2.2% vs. 2.0% vs. 3.2% vs. 2.9%, <jats:italic>P<\/jats:italic> &lt;0.01). Kaplan Meier analysis showed complex lesions (type B2 and C) had lower survival at 12\u2010months (<jats:italic>P<\/jats:italic>\u2009=\u20090.003).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>PCI to more complex lesions continues to be associated with lower procedural success rates as well as inferior medium\u2010term clinical outcomes. Thus the ACC\/AHA lesion classification should still be calculated preprocedure to predict acute PCI success and clinical outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.27411","type":"journal-article","created":{"date-parts":[[2017,11,15]],"date-time":"2017-11-15T10:42:36Z","timestamp":1510742556000},"source":"Crossref","is-referenced-by-count":27,"title":["Utility of the <scp>ACC<\/scp>\/<scp>AHA<\/scp> lesion classification as a predictor of procedural, 30\u2010day and 12\u2010month outcomes in the contemporary percutaneous coronary intervention era"],"prefix":"10.1002","volume":"92","author":[{"given":"James","family":"Theuerle","sequence":"first","affiliation":[{"name":"Department of Cardiology Austin Health Melbourne"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3706-4150","authenticated-orcid":false,"given":"Matias B","family":"Yudi","sequence":"additional","affiliation":[{"name":"Department of Cardiology Austin Health Melbourne"},{"name":"Department of Medicine University of Melbourne Melbourne"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Farouque","sequence":"additional","affiliation":[{"name":"Department of Cardiology Austin Health Melbourne"},{"name":"Department of Medicine University of Melbourne Melbourne"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nick","family":"Andrianopoulos","sequence":"additional","affiliation":[{"name":"Centre of Cardiovascular Research and Education in Therapeutics (CCRE) Monash University Melbourne"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Scott","sequence":"additional","affiliation":[{"name":"Department of Cardiology Austin Health Melbourne"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew E","family":"Ajani","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Melbourne Melbourne"},{"name":"Centre of Cardiovascular Research and Education in Therapeutics (CCRE) Monash University Melbourne"},{"name":"Department of Cardiology Royal Melbourne Hospital Melbourne"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Brennan","sequence":"additional","affiliation":[{"name":"Centre of Cardiovascular Research and Education in Therapeutics (CCRE) Monash University Melbourne"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen J","family":"Duffy","sequence":"additional","affiliation":[{"name":"Centre of Cardiovascular Research and Education in Therapeutics (CCRE) Monash University Melbourne"},{"name":"Department of Cardiovascular Medicine Alfred Hospital Melbourne"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher M","family":"Reid","sequence":"additional","affiliation":[{"name":"Centre of Cardiovascular Research and Education in Therapeutics (CCRE) Monash University Melbourne"},{"name":"School of Public Health Curtin University Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J","family":"Clark","sequence":"additional","affiliation":[{"name":"Department of Cardiology Austin Health Melbourne"},{"name":"Department of Medicine University of Melbourne Melbourne"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the Melbourne Interventional 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